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Chemical Compound Review

Azeserine     (Z)-1-[(2S)-2-amino-2- carboxy-ethoxy]-2...

Synonyms: Azaserin, Azaserina, azaserine, Azaserinum, L-azaserine, ...
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Disease relevance of (E)-2-[(2S)-2-amino-2-carboxy-ethoxy]-2-hydroxy-ethenediazonium

 

Psychiatry related information on (E)-2-[(2S)-2-amino-2-carboxy-ethoxy]-2-hydroxy-ethenediazonium

  • These results suggest that the reduction in the synthesis of PG-H as well as the production of an abnormal form of PG-H during a critical period of limb morphogenesis may be important factors in explaining the micromelia induced by azaserine [6].
 

High impact information on (E)-2-[(2S)-2-amino-2-carboxy-ethoxy]-2-hydroxy-ethenediazonium

 

Chemical compound and disease context of (E)-2-[(2S)-2-amino-2-carboxy-ethoxy]-2-hydroxy-ethenediazonium

 

Biological context of (E)-2-[(2S)-2-amino-2-carboxy-ethoxy]-2-hydroxy-ethenediazonium

 

Anatomical context of (E)-2-[(2S)-2-amino-2-carboxy-ethoxy]-2-hydroxy-ethenediazonium

 

Associations of (E)-2-[(2S)-2-amino-2-carboxy-ethoxy]-2-hydroxy-ethenediazonium with other chemical compounds

 

Gene context of (E)-2-[(2S)-2-amino-2-carboxy-ethoxy]-2-hydroxy-ethenediazonium

 

Analytical, diagnostic and therapeutic context of (E)-2-[(2S)-2-amino-2-carboxy-ethoxy]-2-hydroxy-ethenediazonium

References

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  2. Pathologic and biochemical effects of azaserine in inbred Wistar/Lewis rats and noninbred CD-1 mice. Roebuck, B.D., Lilja, H.S., Curphey, T.J., Longnecker, D.S. J. Natl. Cancer Inst. (1980) [Pubmed]
  3. Secretagogue response of azaserine-induced rat pancreatic acinar tumors in vivo. Herzig, K.H., Creutzfeldt, W., Fölsch, U.R. Gastroenterology (1991) [Pubmed]
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  6. Abnormal synthesis of cartilage-characteristic proteoglycan in azaserine-induced micromelial limbs. Honda, A., Tsuboi, I., Kimata, K., Hirabayashi, Y., Yamada, K., Mori, Y. Biochem. J. (1989) [Pubmed]
  7. High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells. Kolm-Litty, V., Sauer, U., Nerlich, A., Lehmann, R., Schleicher, E.D. J. Clin. Invest. (1998) [Pubmed]
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  9. Effect of dietary intake of fish oil and fish protein on the development of L-azaserine-induced preneoplastic lesions in the rat pancreas. O'Connor, T.P., Roebuck, B.D., Peterson, F., Campbell, T.C. J. Natl. Cancer Inst. (1985) [Pubmed]
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  15. Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein-associated O-GlcNAc. Champattanachai, V., Marchase, R.B., Chatham, J.C. Am. J. Physiol., Cell Physiol. (2007) [Pubmed]
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  21. Response of two rodents, Mastomys natalensis and Mystromys albicaudatus, to the pancreatic carcinogen azaserine. Roebuck, B.D., Longnecker, D.S. J. Natl. Cancer Inst. (1979) [Pubmed]
  22. Photoinhibition of 2-amino-2-carboxybicyclo[2,2,1]heptane transport by O-diazoacetyl-L-serine. An initial step in identifying the L-system amino acid transporter. Segel, G.B., Woodlock, T.J., Murant, F.G., Lichtman, M.A. J. Biol. Chem. (1989) [Pubmed]
  23. Influence of cholecystokinin antagonist on the effects of cholecystokinin and bombesin on azaserine-induced lesions in rat pancreas. Douglas, B.R., Woutersen, R.A., Jansen, J.B., de Jong, A.J., Rovati, L.C., Lamers, C.B. Gastroenterology (1989) [Pubmed]
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  25. Hexosamine-induced fibronectin protein synthesis in mesangial cells is associated with increases in cAMP responsive element binding (CREB) phosphorylation and nuclear CREB: the involvement of protein kinases A and C. Singh, L.P., Andy, J., Anyamale, V., Greene, K., Alexander, M., Crook, E.D. Diabetes (2001) [Pubmed]
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  28. Overexpression of messenger RNA for cholecystokinin-A receptor and novel expression of messenger RNA for gastrin (cholecystokinin-B) receptor in azaserine-induced rat pancreatic carcinoma. Zhou, W., Povoski, S.P., Bell, R.H. Carcinogenesis (1993) [Pubmed]
  29. YfiK from Escherichia coli promotes export of O-acetylserine and cysteine. Franke, I., Resch, A., Dassler, T., Maier, T., Böck, A. J. Bacteriol. (2003) [Pubmed]
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  31. Animal model of human disease. Carcinoma of the pancreas in azaserine-treated rats. Longnecker, D.S. Am. J. Pathol. (1981) [Pubmed]
  32. Gut peptide receptors in pancreata of azaserine-treated and normal control rats. Tang, C., Biemond, I., Appel, M.J., Visser, C.J., Woutersen, R.A., Lamers, C.B. Carcinogenesis (1995) [Pubmed]
  33. Effects of sandostatin, alone and in combination with surgical castration, on pancreatic carcinogenesis in rats and hamsters. Visser, C.J., van Garderen-Hoetmer, A., Klijn, J.G., Foekens, J.A. Int. J. Cancer (1996) [Pubmed]
  34. Modulation of growth and cell turnover of preneoplastic lesions and of prostaglandin levels in rat pancreas by dietary fish oil. Appel, M.J., Woutersen, R.A. Carcinogenesis (1994) [Pubmed]
 
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