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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

purT  -  phosphoribosylglycinamide formyltransferase 2

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK1850, JW1838
 
 
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High impact information on purT

  • However, the purT protein shows significant homology to the purK protein, also involved in purine biosynthesis [1].
  • Two different purT reactions have been characterized: one producing fGAR from ATP, beta-GAR, and formate and the other producing acetyl phosphate and ADP from acetate and ATP [1].
  • The purT GAR transformylase is the first unknown de novo purine biosynthetic enzyme to be discovered in the last 30 years and represents another step forward in understanding cellular control of purine levels [1].

References

  1. Cloning and characterization of a new purine biosynthetic enzyme: a non-folate glycinamide ribonucleotide transformylase from E. coli. Marolewski, A., Smith, J.M., Benkovic, S.J. Biochemistry (1994) [Pubmed]
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