Chemical Compound Review:
Isopurine 7H-purine
Synonyms:
Purine, purin, beta-Purine, purine-ring, SureCN3157, ...
- Presynaptic dopaminergic deficits in Lesch-Nyhan disease. Ernst, M., Zametkin, A.J., Matochik, J.A., Pascualvaca, D., Jons, P.H., Hardy, K., Hankerson, J.G., Doudet, D.J., Cohen, R.M. N. Engl. J. Med. (1996)
- Lasting remissions in hairy-cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine. Piro, L.D., Carrera, C.J., Carson, D.A., Beutler, E. N. Engl. J. Med. (1990)
- Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria. Mandal, M., Boese, B., Barrick, J.E., Winkler, W.C., Breaker, R.R. Cell (2003)
- 2',3'-dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex. A phase I trial. Lambert, J.S., Seidlin, M., Reichman, R.C., Plank, C.S., Laverty, M., Morse, G.D., Knupp, C., McLaren, C., Pettinelli, C., Valentine, F.T. N. Engl. J. Med. (1990)
- Newer purine analogues for the treatment of hairy-cell leukemia. Saven, A., Piro, L. N. Engl. J. Med. (1994)
- Purine phosphoribosyltransferase in gilles de la Tourette syndrome. Van Woert, M.H., Yip, L.C., Balis, M.E. N. Engl. J. Med. (1977)
- Trophic effects of purines in neurons and glial cells. Rathbone, M.P., Middlemiss, P.J., Gysbers, J.W., Andrew, C., Herman, M.A., Reed, J.K., Ciccarelli, R., Di Iorio, P., Caciagli, F. Prog. Neurobiol. (1999)
- Idiopathic uric acid lithiasis: epidemiologic and metabolic aspects. Zechner, O., Pflüger, H., Scheiber, V. J. Urol. (1982)
- Special devices as aids in the management of child self-mutilation in the Lesch-Nyhan syndrome. Letts, R.M., Hobson, D.A. Pediatrics (1975)
- A comparison of the dose response effects of pyrimidine ribonucleosides and adenosine on sleep in rats. Radulovacki, M., Virus, R.M., Rapoza, D., Crane, R.A. Psychopharmacology (Berl.) (1985)
- Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia. Kreitman, R.J., Wilson, W.H., Bergeron, K., Raggio, M., Stetler-Stevenson, M., FitzGerald, D.J., Pastan, I. N. Engl. J. Med. (2001)
- Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain. Correll, C.C., Freeborn, B., Moore, P.B., Steitz, T.A. Cell (1997)
- Modulation of Neisseria porin (PorB) by cytosolic ATP/GTP of target cells: parallels between pathogen accommodation and mitochondrial endosymbiosis. Rudel, T., Schmid, A., Benz, R., Kolb, H.A., Lang, F., Meyer, T.F. Cell (1996)
- The UV response involving the Ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals. Engelberg, D., Klein, C., Martinetto, H., Struhl, K., Karin, M. Cell (1994)
- Myogenic hyperuricemia. A common pathophysiologic feature of glycogenosis types III, V, and VII. Mineo, I., Kono, N., Hara, N., Shimizu, T., Yamada, Y., Kawachi, M., Kiyokawa, H., Wang, Y.L., Tarui, S. N. Engl. J. Med. (1987)
- Hypoxanthine-guanine phosphoribosyltransferase mutant glioma cells: diminished monamine oxidase activity. Skaper, S.D., Seegmiller, J.E. Science (1976)
- Decreased methionine synthesis in purine nucleoside-treated T and B lymphoblasts and reversal by homocysteine. Boss, G.R., Pilz, R.B. J. Clin. Invest. (1984)
- Characterization of the deoxycytidine kinase promoter in human lymphoblast cell lines. Chen, E.H., Johnson, E.E., Vetter, S.M., Mitchell, B.S. J. Clin. Invest. (1995)
- Free radicals and pathogenesis during ischemia and reperfusion of the cat small intestine. Nilsson, U.A., Schoenberg, M.H., Aneman, A., Poch, B., Magadum, S., Beger, H.G., Lundgren, O. Gastroenterology (1994)
- Patterns of lambda Int recognition in the regions of strand exchange. Ross, W., Landy, A. Cell (1983)
- Molecular interactions within the ecdysone regulatory hierarchy: DNA binding properties of the Drosophila ecdysone-inducible E74A protein. Urness, L.D., Thummel, C.S. Cell (1990)
- Organization of minicircle genes for guide RNAs in Trypanosoma brucei. Pollard, V.W., Rohrer, S.P., Michelotti, E.F., Hancock, K., Hajduk, S.L. Cell (1990)
- Complete deficiency of adenine phosphoribosyltransferase. Report of a family. Van Acker, K.J., Simmonds, H.A., Potter, C., Cameron, J.S. N. Engl. J. Med. (1977)
- A mutation in adenylosuccinate lyase associated with mental retardation and autistic features. Stone, R.L., Aimi, J., Barshop, B.A., Jaeken, J., Van den Berghe, G., Zalkin, H., Dixon, J.E. Nat. Genet. (1992)
- Abnormal purine metabolism and purine overproduction in a patient deficient in purine nucleoside phosphorylase. Cohen, A., Doyle, D., Martin, D.W., Ammann, A.J. N. Engl. J. Med. (1976)
- Characterization of a cell culture model for the study of adenosine deaminase- and purine nucleoside phosphorylase-deficient immunologic disease. Ullman, B., Cohen, A., Martin, D.W. Cell (1976)
- Analysis of RNA initiated in isolated mouse myeloma nuclei using purine nucleoside 5'[gamma-S]triphosphates as affinity probes. Smith, M.M., Reeve, A.E., Huang, R.C. Cell (1978)
- Control of nucleolar RNA synthesis by the intracellular pool sizes of ATP and GTP. Grummt, I., Grummt, F. Cell (1976)
- Increased proton conductance pathway in brown adipose tissue mitochondria of rats exhibiting diet-induced thermogenesis. Brooks, S.L., Rothwell, N.J., Stock, M.J., Goodbody, A.E., Trayhurn, P. Nature (1980)
- 5' terminal nucleotide sequences of the messenger RNA's of Dictyostelium discoideum. Dottin, R.P., Weiner, A.M., Lodish, F. Cell (1976)
- A specific partner for abasic damage in DNA. Matray, T.J., Kool, E.T. Nature (1999)
- Convergent and divergent evolution of regulatory sites in eukaryotic phosphorylases. Hwang, P.K., Fletterick, R.J. Nature (1986)
- Novel form of drug-dependence--on adenosine in guinea pig ileum. Collier, H.O., Tucker, J.F. Nature (1983)
- Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. Schumacher, M.A., Choi, K.Y., Zalkin, H., Brennan, R.G. Science (1994)
- Multiple global regulators control HIS4 transcription in yeast. Arndt, K.T., Styles, C., Fink, G.R. Science (1987)
- The genetic and functional basis of purine nucleotide feedback-resistant phosphoribosylpyrophosphate synthetase superactivity. Becker, M.A., Smith, P.R., Taylor, W., Mustafi, R., Switzer, R.L. J. Clin. Invest. (1995)
- The sequence and binding specificity of UaY, the specific regulator of the purine utilization pathway in Aspergillus nidulans, suggest an evolutionary relationship with the PPR1 protein of Saccharomyces cerevisiae. Suárez, T., de Queiroz, M.V., Oestreicher, N., Scazzocchio, C. EMBO J. (1995)
- Mutation of lysine-48 to arginine in the yeast RAD3 protein abolishes its ATPase and DNA helicase activities but not the ability to bind ATP. Sung, P., Higgins, D., Prakash, L., Prakash, S. EMBO J. (1988)
- Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers. Nobori, T., Takabayashi, K., Tran, P., Orvis, L., Batova, A., Yu, A.L., Carson, D.A. Proc. Natl. Acad. Sci. U.S.A. (1996)
- The purine path to chemotherapy. Elion, G.B. Science (1989)
- Bone marrow transplantation only partially restores purine metabolites to normal in adenosine deaminase-deficient patients. Hirschhorn, R., Roegner-Maniscalco, V., Kuritsky, L., Rosen, F.S. J. Clin. Invest. (1981)
- Oxygen metabolites stimulate thromboxane production and vasoconstriction in isolated saline-perfused rabbit lungs. Tate, R.M., Morris, H.G., Schroeder, W.R., Repine, J.E. J. Clin. Invest. (1984)
- Disruption of the purine nucleotide cycle by inhibition of adenylosuccinate lyase produces skeletal muscle dysfunction. Swain, J.L., Hines, J.J., Sabina, R.L., Harbury, O.L., Holmes, E.W. J. Clin. Invest. (1984)