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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

stpA  -  DNA binding protein, nucleoid-associated

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK2663, JW2644, hnsB, hsm-3, rsv
 
 
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Disease relevance of stpA

 

High impact information on stpA

  • In an hns mutant E.coli derivative stpA expression is derepressed, suggesting that regulation of the two genes is coupled [3].
  • We have examined the regulation of the stpA gene, which encodes a protein sharing 58% identity with H-NS, by mRNA analysis and by using stpA-lacZ operon fusions [3].
  • This mutation was a base pair change in the stpA structural gene, and the amino acid substitution in the StpA protein altered its turnover properties, suggesting a role for this residue in a cleavage site for proteolysis [4].
  • The stpA gene, which was localized to 60.24 min on the E. coli chromosome, encodes a 15.3-kDa protein [2].
 

Biological context of stpA

References

 
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