Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

scpB - methylmalonyl-CoA decarboxylase, biotin...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK2915, JW2886, mmcD, ygfG

Aldor, I.S. et al.

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High impact information on scpB

The sbm and ygfG genes encode a novel (2R)-methylmalonyl-CoA mutase and a (2R)-methylmalonyl-CoA decarboxylase, respectively, which convert succinyl-CoA, derived from the tricarboxylic acid cycle, to propionyl-CoA, an essential precursor of 3-hydroxyvalerate (HV) [1].

References

Metabolic engineering of a novel propionate-independent pathway for the production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) in recombinant Salmonella enterica serovar typhimurium. Aldor, I.S., Kim, S.W., Prather, K.L., Keasling, J.D. Appl. Environ. Microbiol. (2002) [Pubmed]

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