Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

glgX - glycogen debranching enzyme

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3417, JW3394

Dauvillée, D. et al., Lim, W.J. et al., Yang, H. et al., Romeo, T. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of glgX

Construction of E. coli strains with defined deletions in the glgX gene is reported here [1].
Cloning and characterization of the glycogen branching enzyme gene existing in tandem with the glycogen debranching enzyme from Pectobacterium chrysanthemi PY35 [2].

High impact information on glgX

A role for the Escherichia coli glgX gene in bacterial glycogen synthesis and/or degradation has been inferred from the sequence homology between the glgX gene and the genes encoding isoamylase-type debranching enzymes; however, experimental evidence or definition of the role of the gene has been lacking [1].
The csrA gene did not affect glycogen debranching enzyme, which is now shown to be encoded by the gene glgX [3].
The region between glgB and glgC contains an open reading frame (ORF) of 1521 bp which we call glgX [4].

References

Role of the Escherichia coli glgX gene in glycogen metabolism. Dauvillée, D., Kinderf, I.S., Li, Z., Kosar-Hashemi, B., Samuel, M.S., Rampling, L., Ball, S., Morell, M.K. J. Bacteriol. (2005) [Pubmed]
Cloning and characterization of the glycogen branching enzyme gene existing in tandem with the glycogen debranching enzyme from Pectobacterium chrysanthemi PY35. Lim, W.J., Park, S.R., Kim, M.K., An, C.L., Yun, H.J., Hong, S.Y., Kim, E.J., Shin, E.C., Lee, S.W., Lim, Y.P., Yun, H.D. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
Coordinate genetic regulation of glycogen catabolism and biosynthesis in Escherichia coli via the CsrA gene product. Yang, H., Liu, M.Y., Romeo, T. J. Bacteriol. (1996) [Pubmed]
Analysis of the Escherichia coli glycogen gene cluster suggests that catabolic enzymes are encoded among the biosynthetic genes. Romeo, T., Kumar, A., Preiss, J. Gene (1988) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.