The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

metR  -  methionine biosynthesis regulon...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3822, JW3804
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of metR


High impact information on metR

  • A plasmid (pRSE562) containing the metE and metR genes of Escherichia coli was used to study the expression of these genes and the role of the MetR protein in regulating metE expression [2].
  • The metR gene was subcloned from pRSE562, and this plasmid, pMRIII, relieved the methionine auxotrophy of a metR mutant after transformation [2].

Chemical compound and disease context of metR


Other interactions of metR

  • When this plasmid was used to transform either wild-type E. coli, metE mutant, or metR mutant, MetE enzyme activity increased 5- to 7-fold over wild-type levels [2].


  1. Structure-function studies on Escherichia coli MetR protein, a putative prokaryotic leucine zipper protein. Maxon, M.E., Wigboldus, J., Brot, N., Weissbach, H. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  2. Regulation of methionine synthesis in Escherichia coli: effect of the MetR protein on the expression of the metE and metR genes. Maxon, M.E., Redfield, B., Cai, X.Y., Shoeman, R., Fujita, K., Fisher, W., Stauffer, G., Weissbach, H., Brot, N. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
WikiGenes - Universities