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Gene Review:

sthA - pyridine nucleotide transhydrogenase, soluble

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3954, JW5551, sth, udhA

Hansen, T. et al., Boonstra, B. et al., Boonstra, B. et al.

Hansen, Schönheit,

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Disease relevance of sthA

The udhA gene of Escherichia coli encodes a soluble pyridine nucleotide transhydrogenase [1].
Cloning of the sth gene from Azotobacter vinelandii and construction of chimeric soluble pyridine nucleotide transhydrogenases [2].

High impact information on sthA

The Escherichia coli strain Pgi-UdhA, a mutant of the strain MG1655, is deficient in both the pgi gene and the udhA gene and cannot grow on glucose as carbon and energy source [3].

References

The udhA gene of Escherichia coli encodes a soluble pyridine nucleotide transhydrogenase. Boonstra, B., French, C.E., Wainwright, I., Bruce, N.C. J. Bacteriol. (1999) [Pubmed]
Cloning of the sth gene from Azotobacter vinelandii and construction of chimeric soluble pyridine nucleotide transhydrogenases. Boonstra, B., Björklund, L., French, C.E., Wainwright, I., Bruce, N.C. FEMS Microbiol. Lett. (2000) [Pubmed]
Escherichia coli phosphoglucose isomerase can be substituted by members of the PGI family, the PGI/PMI family, and the cPGI family. Hansen, T., Schönheit, P. FEMS Microbiol. Lett. (2005) [Pubmed]

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