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Gene Review

ndhD  -  NAD(P)H-quinone oxidoreductase subunit 4

Synechocystis sp. PCC 6803

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Disease relevance of ndhD

  • Five mutants were constructed by inactivating each of the five ndhD genes in Synechocystis sp. strain PCC 6803 [1].

High impact information on ndhD

  • The ndhD gene encodes a membrane protein component of NAD(P)H dehydrogenase [2].
  • The mutant lacking ndhD3 grew much more slowly than the WT at pH 6.5 under 50 ppm CO(2), although other ndhD mutants grew like the WT under these conditions and showed low affinity for CO(2) uptake [1].
  • The ndhD gene is associated with a gene encoding an iron-sulphur protein of photosystem I (psaC) as in plastid DNA [3].
  • Cloning and transcription analysis of the ndh(A-I-G-E) gene cluster and the ndhD gene of the cyanobacterium Synechocystis sp. PCC6803 [3].

Anatomical context of ndhD

  • In contrast to the situation in plastids, psaC and ndhD are not cotranscribed but transcribed from opposite strands [3].


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