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Gene Review:

GCMVs1gp1 - unidentified reading frame (AA 1-2252)

Grapevine chrome mosaic virus

Le Gall, O. et al., Hibrand, L. et al., Ghanem-Sabanadzovic, N.A. et al., Buchhagen, D.L. et al., Demangeat, G. et al.

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Disease relevance of GCMVs1gp1

The primary structure of the polyprotein was compared with that of other viral polyproteins, revealing the same general genetic organization as that of other picorna-like viruses (comoviruses, potyviruses and picornaviruses), except that an additional protein is suspected to occupy the N-terminus of the polyprotein [1].
Immunoprecipitation, kinetic, and biochemical data indicate the this polyprotein contains information that gives rise to the major virion glycoprotein gp85 [2].
In vitro processing of the RNA-2-encoded polyprotein of two nepoviruses: tomato black ring virus and grapevine chrome mosaic virus [3].

High impact information on GCMVs1gp1

All three proteins encoded by GCMV RNA2 (viral coat protein, and the 44K and 46K proteins) were detected by immunoblotting in subcellular fractions prepared from the leaves of infected Chenopodium quinoa plants, confirming a previously proposed model of the GCMV RNA2-encoded polyprotein [4].
These RNAs are 3753 nt (GDefV) and 4607 nt (GARSV) in size and contain a single open reading frame encoding a polyprotein of 122 kDa (GDefV) and 150 kDa (GARSV) [5].

References

Nucleotide sequence of Hungarian grapevine chrome mosaic nepovirus RNA1. Le Gall, O., Candresse, T., Brault, V., Dunez, J. Nucleic Acids Res. (1989) [Pubmed]
Intracellular precursors to the major glycoprotein of avian oncoviruses in chicken embryo fibroblasts. Buchhagen, D.L., Hanafusa, H. J. Virol. (1978) [Pubmed]
In vitro processing of the RNA-2-encoded polyprotein of two nepoviruses: tomato black ring virus and grapevine chrome mosaic virus. Demangeat, G., Hemmer, O., Fritsch, C., Le Gall, O., Candresse, T. J. Gen. Virol. (1991) [Pubmed]
Immunodetection of the proteins encoded by grapevine chrome mosaic nepovirus RNA2. Hibrand, L., Le Gall, O., Candresse, T., Dunez, J. J. Gen. Virol. (1992) [Pubmed]
Complete nucleotide sequence of the RNA-2 of grapevine deformation and Grapevine Anatolian ringspot viruses. Ghanem-Sabanadzovic, N.A., Sabanadzovic, S., Digiaro, M., Martelli, G.P. Virus Genes (2005) [Pubmed]

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