Gene Review:
SMG7 - SMG7 nonsense mediated mRNA decay factor
Homo sapiens
Synonyms:
C1orf16, EST1-like protein C, EST1C, KIAA0250, Protein SMG7, ...
- SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. Fukuhara, N., Ebert, J., Unterholzner, L., Lindner, D., Izaurralde, E., Conti, E. Mol. Cell (2005)
- SMG7 acts as a molecular link between mRNA surveillance and mRNA decay. Unterholzner, L., Izaurralde, E. Mol. Cell (2004)
- Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7. Ohnishi, T., Yamashita, A., Kashima, I., Schell, T., Anders, K.R., Grimson, A., Hachiya, T., Hentze, M.W., Anderson, P., Ohno, S. Mol. Cell (2003)