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MeSH Review

Schizoid Personality Disorder

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Psychiatry related information on Schizoid Personality Disorder


High impact information on Schizoid Personality Disorder

  • RESULTS: The SHAPS non-psychopaths and those with schizoid personality disorders had enhanced 5-HT function (prolactin response to d-fenfluramine) [2].
  • Although paranoid symptoms and premorbid schizoid personality did not differentiate the two groups, nonschizoid patients who were nonparanoid tended to be in the PLD group while nonschizoid patients who were paranoid tended to be in the HCD group [3].
  • Paranoid or schizoid personality disorders is also associated with a polymorphism of the DRD2, which might be associated with a previously demonstrated low density of this receptor [4].
  • A previous investigation gave no evidence of a significant relationship of patterns of adaptation to conflict, as measured with the Serial Color-Word Test, with the Schizoid Personality Scale of the Coolidge Axis II Inventory [5].
  • "Schizoid" personality in childhood: auditory P300 and eye tracking responses at follow-up in adult life [6].

Biological context of Schizoid Personality Disorder


Gene context of Schizoid Personality Disorder

  • A two-factor varimax solution yielded a first factor accounting for 49 per cent of total unrotated variance with high (0.70 to 0.91) loadings from Hallucinatory predisposition, Perceptual aberration, Schizophrenism, STA and STB scales, and was interpreted as reflecting a general factor of schizoid personality disorder [7].


  1. Dimensions of personality disorders in offenders. Ullrich, S., Marneros, A. Criminal behaviour and mental health : CBMH. (2004) [Pubmed]
  2. Relationship between 5-HT function and impulsivity and aggression in male offenders with personality disorders. Dolan, M., Anderson, I.M., Deakin, J.F. The British journal of psychiatry : the journal of mental science. (2001) [Pubmed]
  3. The relationship of demographic, clinical, and outcome variables to neuroleptic treatment requirements. Young, M.A., Meltzer, H.Y. Schizophrenia bulletin. (1980) [Pubmed]
  4. Polymorphism in exon 6 of the dopamine D(2) receptor gene (DRD2) is associated with elevated blood pressure and personality disorders in men. Rosmond, R., Rankinen, T., Chagnon, M., Pérusse, L., Chagnon, Y.C., Bouchard, C., Björntorp, P. Journal of human hypertension. (2001) [Pubmed]
  5. Patterns of adaptation to conflict and schizoid personality scale scores. Rubino, I.A., Mascis, M.C., Siracusano, A. Psychological reports. (2006) [Pubmed]
  6. "Schizoid" personality in childhood: auditory P300 and eye tracking responses at follow-up in adult life. Blackwood, D.H., Muir, W.J., Roxborough, H.M., Walker, M.R., Townshend, R., Glabus, M.F., Wolff, S. Journal of autism and developmental disorders. (1994) [Pubmed]
  7. Factors of schizoid personality. Raine, A., Allbutt, J. The British journal of clinical psychology / the British Psychological Society. (1989) [Pubmed]
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