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MeSH Review

Mitral Valve Prolapse

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Disease relevance of Mitral Valve Prolapse

  • In addition to the presence of prolapse and regurgitation, the assessment of leaflet thickness, leaflet length, annular diameter, and chordal length is fundamental to the definition and stratification of patients with MVP associated with the floppy mitral valve [1].
  • Certain normal aging changes may mimic heart disease: sigmoid-shaped ventricular septum (hypertrophic cardiomyopathy), mitral leaflet "buckling" (floppy mitral valve) [2].

High impact information on Mitral Valve Prolapse


Analytical, diagnostic and therapeutic context of Mitral Valve Prolapse


  1. Spectrum of structural abnormalities in floppy mitral valve echocardiographic evaluation. Malkowski, M.J., Boudoulas, H., Wooley, C.F., Guo, R., Pearson, A.C., Gray, P.G. Am. Heart J. (1996) [Pubmed]
  2. The old-age heart: normal aging changes which can produce or mimic cardiac disease. Waller, B.F. Clinical cardiology. (1988) [Pubmed]
  3. Bacterial endocarditis in subjects 60 years of age and older. Thell, R., Martin, F.H., Edwards, J.E. Circulation (1975) [Pubmed]
  4. Floppy mitral valve and ventricular septal defect: an anatomic study. Lucas, R.V., Edwards, J.E. J. Am. Coll. Cardiol. (1983) [Pubmed]
  5. An unusual renal complication in a patient with osteogenesis imperfecta. Butani, L., Rosekrans, J.A., Morgenstern, B.Z., Milliner, D.S. Am. J. Kidney Dis. (1995) [Pubmed]
  6. Systolic anterior motion of the mitral chordae tendineae: prevalence and clinical and Doppler-echocardiographic features. Pearson, A.C., Pasierski, T.J., Orsinelli, D.A., Gray, P., Huschart, K. Am. Heart J. (1996) [Pubmed]
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