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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Drug Labeling

 
 
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High impact information on Drug Labeling

  • It has been previously shown that photoaffinity drug-labeling sites reside within, or near, the last transmembrane loop of each cassette within P-glycoprotein (transmembrane domains (TM) 5-6 and 11-12) [1].
  • Major photoaffinity drug labeling sites for iodoaryl azidoprazosin in P-glycoprotein are within, or immediately C-terminal to, transmembrane domains 6 and 12 [2].
  • The intravitreal injection of the labeling drug was preceded by treatment with the neurotoxic dopamine-analogue, 6-hydroxydopamine, in order to destroy the otherwise interfering dopaminergic processes [3].
  • Drug labeling calls for intravenous amiodarone to be administered over 10 minutes [4].
  • American Academy of Veterinary Pharmacology and Therapeutics: perspectives on the utility of flexible drug labeling. An AAVPT perspective: Part I [5].
 

Associations of Drug Labeling with chemical compounds

References

  1. Functional evidence that transmembrane 12 and the loop between transmembrane 11 and 12 form part of the drug-binding domain in P-glycoprotein encoded by MDR1. Zhang, X., Collins, K.I., Greenberger, L.M. J. Biol. Chem. (1995) [Pubmed]
  2. Major photoaffinity drug labeling sites for iodoaryl azidoprazosin in P-glycoprotein are within, or immediately C-terminal to, transmembrane domains 6 and 12. Greenberger, L.M. J. Biol. Chem. (1993) [Pubmed]
  3. Electron microscopical observations on the indoleamine-accumulating neurons and their synaptic connections in the retina of the cat. Holmgren-Taylor, I. J. Comp. Neurol. (1982) [Pubmed]
  4. Lack of a hypotensive effect with rapid administration of a new aqueous formulation of intravenous amiodarone. Somberg, J.C., Timar, S., Bailin, S.J., Lakatos, F., Haffajee, C.I., Tarjan, J., Paladino, W.P., Sarosi, I., Kerin, N.Z., Borbola, J., Bridges, D.E., Molnar, J. Am. J. Cardiol. (2004) [Pubmed]
  5. American Academy of Veterinary Pharmacology and Therapeutics: perspectives on the utility of flexible drug labeling. An AAVPT perspective: Part I. Koritz, G.D. J. Am. Vet. Med. Assoc. (1995) [Pubmed]
  6. Changes in drug labelling. Letter to all practitioners. Simpson, P.J., Birks, R.J. SAAD digest. (2004) [Pubmed]
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