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MeSH Review

Hemorrhagic Fevers, Viral

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Disease relevance of Hemorrhagic Fevers, Viral


High impact information on Hemorrhagic Fevers, Viral

  • The use of a formalin-fixed skin specimen for laboratory confirmation of EHF can provide an appropriate method for EHF surveillance when linked with physician training, use of viral hemorrhagic fever isolation precautions, and follow-up investigation [3].
  • Inhibition of Crimean-Congo hemorrhagic fever viral infectivity yields in vitro by ribavirin [4].
  • It will be of interest to establish whether other viral hemorrhagic fevers involve the same target cells as in DHF/DSS and are mediated by similar effector mechanisms [5].


  1. Stampidine prevents mortality in an experimental mouse model of viral hemorrhagic fever caused by lassa virus. Uckun, F.M., Petkevich, A.S., Vassilev, A.O., Tibbles, H.E., Titov, L. BMC Infect. Dis. (2004) [Pubmed]
  2. Emerging roles of tissue factor in viral hemorrhagic fever. Ruf, W. Trends Immunol. (2004) [Pubmed]
  3. Long-term disease surveillance in Bandundu region, Democratic Republic of the Congo: a model for early detection and prevention of Ebola hemorrhagic fever. Lloyd, E.S., Zaki, S.R., Rollin, P.E., Tshioko, K., Bwaka, M.A., Ksiazek, T.G., Calain, P., Shieh, W.J., Kondé, M.K., Verchueren, E., Perry, H.N., Manguindula, L., Kabwau, J., Ndambi, R., Peters, C.J. J. Infect. Dis. (1999) [Pubmed]
  4. Inhibition of Crimean-Congo hemorrhagic fever viral infectivity yields in vitro by ribavirin. Watts, D.M., Ussery, M.A., Nash, D., Peters, C.J. Am. J. Trop. Med. Hyg. (1989) [Pubmed]
  5. Antibody, macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade. Halstead, S.B. Rev. Infect. Dis. (1989) [Pubmed]
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