Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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MeSH Review:

Scheuermann's Disease

Karppinen, J. et al., Graat, H.C. et al.

Karppinen, Pääkkö, Paassilta, Lohiniva, Kurunlahti, Tervonen, Nieminen, Göring, Malmivaara, Vanharanta, Ala-Kokko,

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High impact information on Scheuermann's Disease

CONCLUSION: The results of this study indicate that the presence of Trp3 allele is associated with Scheuermann disease and intervertebral disk degeneration [1].
When compared with the matched control subjects, they had an increased likelihood of Scheuermann disease (P =.035) and an increased number of degenerated disks from T11 to S1 (P =.021) [1].
STUDY DESIGN: Classic cases of Scheuermann disease in male monozygotic twins are reported [2].

References

Radiologic phenotypes in lumbar MR imaging for a gene defect in the COL9A3 gene of type IX collagen. Karppinen, J., Pääkkö, E., Paassilta, P., Lohiniva, J., Kurunlahti, M., Tervonen, O., Nieminen, P., Göring, H.H., Malmivaara, A., Vanharanta, H., Ala-Kokko, L. Radiology. (2003) [Pubmed]
Classical Scheuermann disease in male monozygotic twins: further support for the genetic etiology hypothesis. Graat, H.C., van Rhijn, L.W., Schrander-Stumpel, C.T., van Ooij, A. Spine. (2002) [Pubmed]

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