Disease relevance of Classic

• PURPOSE: Classic Kaposi's sarcoma (KS) is rare in children [1].
• The search for the genetic lesion in Ashkenazi Jews with Classic Tay-Sachs disease [2].
• BACKGROUND: Classic chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) patients have prominent proximal and distal weakness [3].
• Phylogenetic analysis confirmed that SNV-like hantaviruses are widely distributed in Peromyscus species rodents throughout North America. Classic SNV is the major cause of HPS in North America, but other Peromyscine-borne hantaviruses, e.g., New York and Monongahela viruses, are also associated with HPS cases [4].
• Why are strokes related to hypertension? Classic studies and hypotheses revisited [5].

Psychiatry related information on Classic

• BACKGROUND: Classic GSS is characterized by an early age at onset, prominent cerebellar signs with a slowly evolving dementia, and a neuropathology including multifocal PrP-positive plaques and variable but usually modest spongiform change [6].
• In a study of the MMPI personality types of hospitalized men and women alcoholics, the Neurotic and Classic types had the characteristics of reactive alcoholism, and the Psychopathic, Schizoform A and Schizoform B types had the characteristics of essential alcoholism [7].
• Folie à deux - a mad family. (Classic Text No.35, with introduction by G.E. Berrios) [8].
• Seignot's paper on the treatment of Tourette's syndrome with haloperidol. Classic Text No. 31 [9].

High impact information on Classic

• Here we report the 2.8 A resolution crystal structure of yeast AHAS in complex with a sulfonylurea herbicide, chlorimuron ethyl [10].
• One hundred fifty-seven sera from 120 patients with SLE were examined for classic (c) and perinuclear (p) pattern ANCA by indirect immunofluorescence [11].
• Gene-expression profiling reveals distinct expression patterns for Classic versus Variant Merkel cell phenotypes and new classifier genes to distinguish Merkel cell from small-cell lung carcinoma [12].
• We assume that the differential expression levels of some of these genes reflect, analogous to SCLC, the different biological and clinical properties of Classic and Variant MCC phenotypes [12].
• BACKGROUND: Classic fat balance studies detect fat malabsorption but do not discriminate between the potential causes of malabsorption, such as impaired intestinal lipolysis or reduced uptake of fatty acids [13].

Chemical compound and disease context of Classic

• The first known document on epilepsy in China appeared in The Yellow Emperor's Classic of Internal Medicine, Huang Di Nei Ching, written by a group of physicians around 770-221 B.C. The description of epilepsy in this book and in many others later published was confined to generalized convulsive seizures [14].
• At the high concentration of added cadmium or copper, joint toxicity of chlorimuron-ethyl and the heavy metals was more dependent on the concentrations of the latter [15].
• The Classic: amputation and adriamycin in primary osteosarcoma. 1974 [16].
• These levels of edema were associated with a 40 percent incidence of striae with Mystique (17/43), 14 percent with the CV Classic (3/21 eyes), 5 percent with Durasoft 3 clear (1/22 eyes) and 2 percent with Durasoft 3 opaque lenses (1/44 eyes) [17].

Biological context of Classic

• A plasmid containing the large and small subunit genes of AHAS II was mutagenized using hydroxylamine and clones resistant to the sulphonylurea chlorimuron ethyl were selected [18].
• Differentiation-Specific Factors Modulate Epidermal CYP1-4 Gene Expression in Human Skin in Response to Retinoic Acid and Classic Aryl Hydrocarbon Receptor Ligands [19].
• OBJECTIVES: Classic histological grading and molecular genetic analysis of epithelial hyperplastic laryngeal lesions (EHLL) were correlated in an attempt to elucidate, which classic marker reflects best the gradual progression of laryngeal premalignant lesions as determined by an increasing number of molecular genetic aberrations [20].
• CONCLUSIONS: Classic testicular seminomas are aneuploid tumors [21].
• Between 1972 and 1985, 82 Classic Kaposi's Sarcomas were treated by radiotherapy in the Division of Radiation Oncology at NYU Medical Center. Doses ranged from 650 cGy in 1 fraction to 3,500 cGy in 10 fractions, reflecting the judgement of the responsible physician [22].

Anatomical context of Classic

• PURPOSE: Classic studies have demonstrated that corneal epithelial cell density in culture can alter the balance of stimulatory and inhibitory cytokines controlling the elaboration of collagenolytic activity by co-cultured stromal cells [23].
• Low T Cell Responses to Human Herpesvirus 8 in Patients with AIDS-Related and Classic Kaposi Sarcoma [24].
• Medial deviation of the popliteal artery was evident in six of 14 patent popliteal arteries, and lateral deviation was observed in one limb. "Classic" abrupt medial angulation of the popliteal artery was observed in one limb [25].
• BACKGROUND: Classic first-stage Norwood repair of hypoplastic left heart syndrome uses a homograft patch enlargement to obtain an unobstructed aorta and coronary arteries [26].
• Urinary tract stone disease. Classic studies [27].

Associations of Classic with other chemical compounds

• Dose-response trends were observed for chlorimuron-ethyl, chlorpyrifos, and phorate; the strongest odds ratio was for applying chlorpyrifos on more than 40 days per year (OR = 2.40, 95% CI: 1.24, 4.65) [28].
• The odds ratios for four organophosphate insecticides (terbufos, fonofos, chlorpyrifos, and phorate) were elevated when these chemicals were modeled individually and remained elevated, though attenuated somewhat, when chlorimuron-ethyl was included [28].
• BACKGROUND: A new laryngeal mask airway, the ProSeal (PLMA), is said to be more difficult to insert than the laryngeal mask airway Classic (CLMA) using propofol anaesthesia [29].
• High concentration potassium permanganate eliminates protein and particle contamination of the reusable Classic laryngeal mask airway [30].
• Cuff pressure increases within 5 min of nitrous oxide exposure were > 250% in the Classic LMA and were not significantly different from those found in the Marshall laryngeal mask airway [31].

Gene context of Classic

• RESULTS: Classic plasma markers of endothelial injury, tPA and sTM significantly elevated in SARS patients in comparison to controls [t-PA: 1.48 +/- 0.16 nmol/L versus 0.25 +/- 0.03 nmol/L (P<0.0001), and sTM: 0.26 +/- 0.06 nmol/L versus 0.14 +/- 0.02 nmol/L (P<0.05)] [32].
• In humans, deficiency of galactose-1-phosphate uridyltransferase (GALT) can lead a metabolic disorder Classic Galactosemia [33].
• In these conditions, we classified and quantified three pathological structures associated to the neuritic degenerative process: 1) Amyloid-beta deposits (AbetaDs), 2) Classic neuritic plaques (NPs), and 3) Dystrophic neurites clusters (DNCs) lacking amyloid-beta deposits [34].
• The classic (C) MCs of normal salivary glands stained by IMP with antibodies to cytokeratin and S100 protein and stained by IMF with the same antibodies and with antibodies to vimentin and actin [35].
• Molecular Analysis of the CLCNKB Gene in Japanese Patients with Classic Bartter Syndrome [36].

Analytical, diagnostic and therapeutic context of Classic

• DESIGN: Classic twin study [37].
• PURPOSE: Classic inguinal lymphadenectomy for penile cancer is associated with significant immediate and long-term sequelae limiting its use in the prophylactic setting [38].
• The influence of dose on the long-term control of Classic (non-AIDS associated) Kaposi's sarcoma by radiotherapy [22].
• CONCLUSIONS: Classic laparoscopic donor and hand assisted laparoscopic donor nephrectomies appear to be safe procedures for harvesting kidneys [39].
• We therefore conclude that doses of this magnitude are appropriate for the long-term care of Classic Kaposi's sarcoma [22].

References