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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Primate T-lymphotropic virus 3

 
 
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Disease relevance of Primate T-lymphotropic virus 3

  • PCR amplification of pol and tax regions, using HTLV-1, -2 and STLV-3 highly conserved primers, demonstrated the presence of a new human retrovirus in one DNA sample. tax (180 bp) and pol (318 bp) phylogenetic analyses demonstrated the strong relationships between the novel human strain (Pyl43) and STLV-3 isolates from Cameroon [1].
 

High impact information on Primate T-lymphotropic virus 3

  • Molecular clock analysis of env estimated that STLV-3/CTO-NG409 diverged from East and West/Central African STLV-3s about 140,900+/-12,400 years ago, suggesting an ancient African origin of STLV-3 [2].

References

  1. Discovery of a new human T-cell lymphotropic virus (HTLV-3) in Central Africa. Calattini, S., Chevalier, S.A., Duprez, R., Bassot, S., Froment, A., Mahieux, R., Gessain, A. Retrovirology (2005) [Pubmed]
  2. A novel, divergent simian T-cell lymphotropic virus type 3 in a wild-caught red-capped mangabey (Cercocebus torquatus torquatus) from Nigeria. Meertens, L., Shanmugam, V., Gessain, A., Beer, B.E., Tooze, Z., Heneine, W., Switzer, W.M. J. Gen. Virol. (2003) [Pubmed]
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