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MeSH Review:

Lactose Intolerance

Johnson, J.D. et al., Farup, P.G. et al., Vonk, R.J. et al., Yang, Y. et al., Devogelaer, J.P. et al.

Vonk, Priebe, Koetse, Stellaard, Lenoir-Wijnkoop, Antoine, Zhong, Huang,

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High impact information on Lactose Intolerance

Lactose loading tests and other means were used to determine the pattern of primary "adult" lactose malabsorption (LM) and milk use among 171 subjects, including 122 children and 49 adults, almost all of them Pima Indians of Arizona. LM develops at quite young ages in full-blooded Pima children: already in the 3- to 4-year age group, 40% had LM [1].
Lactose intolerance (LI) predisposes to reduced perimenopausal BMD [2].
BACKGROUND: We studied the degree of lactose digestion and orocecal transit time (OCTT) as possible causes for the variability of symptoms of lactose intolerance (LI) in a sample of a population with genetically determined low lactase activity [3].
The aims of this study were to compare the prevalence of lactose malabsorption (LM) and symptoms related to intake of milk and lactose in subjects with IBS with that of healthy volunteers, and to search for symptoms that are characteristic of LM [4].
OBJECTIVE: To determine lactose metabolism and lactase activity in Chinese children of different ages, prevalence of lactase deficiency (LD), and lactose intolerance (LI) [5].

References

Lactose malabsorption among the Pima indians of Arizona. Johnson, J.D., Simoons, F.J., Hurwitz, R., Grange, A., Mitchell, C.H., Sinatra, F.R., Sunshine, P., Robertson, W.V., Bennett, P.H., Kretchmer, N. Gastroenterology (1977) [Pubmed]
Lactose intolerance (LI) predisposes to reduced perimenopausal BMD. Devogelaer, J.P., Faille, I., Mainguet, P. Bone (1997) [Pubmed]
Lactose intolerance: analysis of underlying factors. Vonk, R.J., Priebe, M.G., Koetse, H.A., Stellaard, F., Lenoir-Wijnkoop, I., Antoine, J.M., Zhong, Y., Huang, C.Y. Eur. J. Clin. Invest. (2003) [Pubmed]
Lactose malabsorption in a population with irritable bowel syndrome: prevalence and symptoms. A case-control study. Farup, P.G., Monsbakken, K.W., Vandvik, P.O. Scand. J. Gastroenterol. (2004) [Pubmed]
The prevalence of lactase deficiency and lactose intolerance in Chinese children of different ages. Yang, Y., He, M., Cui, H., Bian, L., Wang, Z. Chin. Med. J. (2000) [Pubmed]

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