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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

A new antibiotic nortriterpene quinone methide from Maytenus catingarum.

15alpha-Hydroxy-21-keto-pristimerine (1), a new nortriterpene quinone methide was isolated from the root bark of Maytenus catingarum along with other well-known related compounds, including pristimerine (2), tingenone, and 20alpha-hydroxy-tingenone. The structure of 1 was determined by means of 1H and 13C NMR spectroscopy, including homonuclear and heteronuclear correlations. Compound 1 showed antibiotic activity against Gram-positive bacteria.[1]


  1. A new antibiotic nortriterpene quinone methide from Maytenus catingarum. Alvarenga, N.L., Velázquez, C.A., Gómez, R., Canela, N.J., Bazzocchi, I.L., Ferro, E.A. J. Nat. Prod. (1999) [Pubmed]
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