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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

cDNA cloning and sequence analysis of bubaline growth hormone.

The cDNA for Bubalus bubalis growth hormone ( GH) has been cloned and sequence determined through RT-PCR approach. The nucleotide sequence of bubaline GH cDNA was in a single reading frame coding for a protein of 191 residues comprising a putative signal sequence of 27 amino acids. Homology comparison of the sequence with other mammalian GH cDNAs showed a very high degree of evolutionary conservation. Bubaline GH sequence shared a homology of 99.5%, 99.5%, 98.6%, 87.6% and 61.9% with that of ovine, caprine, bovine, porcine and human, respectively at amino acid level.[1]


  1. cDNA cloning and sequence analysis of bubaline growth hormone. Verma, S., Ghorpade, A., Tiwari, G., Das, P., Garg, L.C. DNA Seq. (1999) [Pubmed]
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