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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis.

Ethylene regulates plant growth, development, and responsiveness to a variety of stresses. Cloning of the Arabidopsis EIN2 gene identifies a central component of the ethylene signaling pathway. The amino-terminal integral membrane domain of EIN2 shows similarity to the disease-related Nramp family of metal-ion transporters. Expression of the EIN2 CEND is sufficient to constitutively activate ethylene responses and restores responsiveness to jasmonic acid and paraquat-induced oxygen radicals to mutant plants. EIN2 is thus recognized as a molecular link between previously distinct hormone response pathways. Plants may use a combinatorial mechanism for assessing various stresses by enlisting a common set of signaling molecules.[1]

References

  1. EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis. Alonso, J.M., Hirayama, T., Roman, G., Nourizadeh, S., Ecker, J.R. Science (1999) [Pubmed]
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