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Mathieu, D. et al.

Mathieu, Coffin, Kobeiter, Caseiro-Alves, Mahfouz, Rahmouni, Diche,

Unexpected MR-T1 enhancement of endocrine liver metastases with mangafodipir.

With the use of available liver magnetic resonance contrast agents, such as mangafodipir (Mn-DPDP), liver metastases do not exhibit enhancement on T1-weighted images. This absence of enhancement is due to the lack of hepatocytes within these tumors. The purpose of this report is to demonstrate an unexpected enhancement on T1-weighted images 30 minutes after injection of mangafodipir, in the case of endocrine liver metastases from a non-hyperfunctioning neuroendocrine pancreatic tumor. Different hypotheses could explain this unexpected enhancement, such as increased arterial tumoral flow or high metabolic activity. Contrary to liver metastases of other origins, Mn-DPDP enhancement can be present in neuroendocrine metastases. J. Magn. Reson. Imaging 1999;10:193-195.[1]

References

Unexpected MR-T1 enhancement of endocrine liver metastases with mangafodipir. Mathieu, D., Coffin, C., Kobeiter, H., Caseiro-Alves, F., Mahfouz, A., Rahmouni, A., Diche, T. Journal of magnetic resonance imaging : JMRI. (1999) [Pubmed]

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