The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Bacterial leakage versus dye leakage in obturated root canals.

AIM: The aim of this study was to compare in vitro bacterial and dye leakage tests, commonly used to determine the seal of root canal fillings. METHODOLOGY: Ninety-six single-rooted teeth had their crowns removed at the cemento-enamel junction and their roots instrumented to ISO size 60 within 1 mm of the apex. Three groups of 30 roots were obturated by lateral condensation using gutta-percha and one or other of the sealers. AH26, Ketac Endo, or Roth's 801 sealer. Three roots were used as negative controls and three roots as positive controls. The roots were then exposed at their coronal end first for 38 days to soy broth containing Staphylococcus epidermidis and thereafter for 48 h to basic fuchsin. Bacterial leakage was recorded when the challenging organism could be recovered from the apical end. Dye leakage was checked by microscopy of transverse sections of the apical tip at the end of the experiment. RESULTS: For the bacterial experiment, there was no significant difference amongst the three sealer groups. The dye experiment showed significantly greater leakage in the AH26 compared to the Ketac Endo group. No correlation between the results of the two tests could be seen. CONCLUSIONS: The results of this study suggest that the molecular size of the penetrating agent may not be the relevant parameter when attempting to determine an appropriate test for the sealability of root canal fillings.[1]


  1. Bacterial leakage versus dye leakage in obturated root canals. Barthel, C.R., Moshonov, J., Shuping, G., Orstavik, D. International endodontic journal. (1999) [Pubmed]
WikiGenes - Universities