Disease relevance of Dental Pulp Cavity

• Peritubular dentin was not found, but hydroxyapatite deposition in the dentinal tubular lumens was observed, whereas typical denticles with dentinal tubules and hydroxyapatite deposits were located in the pulp chambers [1].
• BACKGROUND AND OBJECTIVES: Smear layer removal with EDTA from root canal walls allows greater cleaning and disinfection of root canals [2].
• Identification by nested polymerase chain reaction was performed in root canal samples from teeth associated with either asymptomatic periradicular lesions or acute apical periodontitis [3].
• Anaphylaxis due to formaldehyde released from root-canal disinfectant [4].
• Contact urticaria from formaldehyde in a root-canal dental paste [5].

High impact information on Dental Pulp Cavity

• Herein, we report the generation of Dspp-null mice that develop tooth defects similar to human dentinogenesis imperfecta III with enlarged pulp chambers, increased width of predentin zone, hypomineralization, and pulp exposure [6].
• Dental abnormalities included root stunting, microdontia, hypodontia, taurodontia (enlarged pulp chambers), and over-retention of primary teeth [7].
• The results demonstrated that after infection, the proportion of the root canal flora represented by the four pathogens was almost identical in both groups (39.9 and 42.2% for RAG-2 and immunocompetent control mice, respectively) [8].
• It was found that although tooth size in the FD patients was smaller than normal, the enamel was thicker on the occlusal table, while the pulp chamber was smaller and disproportional to tooth size [9].
• Prevention of the epoxy resin-based root canal sealers-induced cyclooxygenase-2 expression and cytotoxicity of human osteoblastic cells by various antioxidants [10].

Chemical compound and disease context of Dental Pulp Cavity

• We reviewed the literature describing cases with anaphylaxis/angioedma caused by formaldehyde in root canal disinfectants and found that about 1/2 of the reported cases developed symptoms over 2 h after dental treatment [4].
• The inhibition of growth of Streptococcus anginosus (milleri) by three calcium hydroxide sealers--calciobiotic root canal sealer (Hygienic Corporation, Akron, OH), Sealapex (Kerr Division, Sybron Corporation, Romulus, MI), and Apexit (Vivadent, USA, Amherst, NY)--was compared with a zinc oxide-eugenol sealer: Roth (Roth International, Chicago, IL) [11].
• Cultivable microbial flora associated with persistent periapical disease and coronal leakage after root canal treatment: a preliminary study [12].
• The aim of this scanning electron microscopic study was to compare the quality and amount of smear layer generated in the apical third of straight root canals by 2 rotary nickel-titanium reamers and 1 rotary steel reamer with different cutting blade designs [13].
• The root canal of the supernumerary tooth was prepared using the step back technique and copious irrigation with 2.6% sodium hypochlorite [14].

Biological context of Dental Pulp Cavity

• In addition, GSH depletion, but not the attack of oxygen free radicals, could be the mechanism for epoxy resin-based root canal sealers-induced cytotoxicity and COX-2 mRNA gene expression [10].
• Antibody formation to dog pulp tissue altered by eugenol within the root canal [15].
• Radiographs were taken biweekly and at the first signs of inflammatory root resorption or at 4 weeks, the root canals were fully instrumented and medicated with calcium hydroxide [16].
• Susceptibility of a polycaprolactone-based root canal filling material to degradation. II. Gravimetric evaluation of enzymatic hydrolysis [17].
• All glutaraldehyde solutions tested may be used in endodontic practice for rapid decontamination of gutta-percha cones, thus contributing to the maintenance of the aseptic chain, an essential factor for successful root canal treatment [18].

Anatomical context of Dental Pulp Cavity

• The radiopaque markers, which are composed of small pieces of root canal broach inserted into the muscle belly, make it possible to determine longitudinal masseter muscle growth as well as migration of the masseter muscle relative to the mandible [19].
• Fate of 14C-labelled dimethylpolysiloxane (silicone oil) in a root canal filling material embedded in rat subcutaneous tissues [20].
• Pulp chambers of extracted third molars were filled with one of the following medicaments: gutta-percha with Roth's zinc oxide and eugenol-based sealer, warm gutta-percha with sealer, warm gutta-percha without sealer, calcium hydroxide, formocresol, cotton pellet, or left empty [21].
• CONCLUSIONS: It is suggested that LPS released from the infected root canal triggers the synthesis of IL-1 alpha and TNF-alpha from macrophages [22].
• The post-space was made in five extracted human molars with obturated root canals, and the indirect resin core was produced on a gypsum model [23].

Associations of Dental Pulp Cavity with chemical compounds

• Given the mechanical and rheological properties of this new DCPD/CaO-based cement, its use as root canal sealing material can be considered as classical calcium hydroxide or ZnO/eugenol-based pastes, without or with a gutta-percha point [24].
• At 2 weeks, formations of hard tissue, with few cells in the root canals and bone-like tissue in the coronal pulp chamber, were noted [25].
• The mutagenic potential of 12 commercially available dental cements and of two 'pure substances' (zinc oxide and eugenol) used in root canal filling were examined [26].
• Factors that induce GSH synthesis may appear useful in preventing cell damage mediated by epoxy resin-based root canal sealers [10].
• Root canal sealers containing formaldehyde and bisphenol A diglyether proved to be not only cytotoxic but also genotoxic [27].

Gene context of Dental Pulp Cavity

• PE samples were collected from root canals during routine endodontic treatments, and the enzyme-linked immunosorbent assay was used to measure PE-IL-1 beta and IL-1ra [28].
• However, little is known about whether chemical interaction can modulate the COX-2 expression and cytotoxicity induced by formaldehyde-containing-ZOE-based root canal sealers [29].
• RESULTS: The periapical exudate samples demonstrated marked differences in MMP-8 levels between the teeth in the first visit and significant decrease in MMP-8 levels during the root-canal treatment (P = 0.0107) [30].
• The aim of this study was to investigate the effects of root canal sealers N2 (zinc-oxide eugenol based) and AH Plus (epoxy resin based) on the expression of IL-6 and IL-8 mRNA gene in human osteoblastic cell line U2OS cells [31].
• AIM: To study the presence, levels and molecular forms of matrix metalloproteinase (MMP) -8 (collage-nase-2) in pulpal and periapical inflammation, and the changes in MMP-8 levels in root-canal exudates during root-canal treatment [30].

Analytical, diagnostic and therapeutic context of Dental Pulp Cavity

• The disodium salt of ethylenediamine tetraacetate (EDTA) is a calcium ion chelator used in endodontics to enlarge root canals [32].
• In method 2, a low-concentration (0.5%) sodium hypochlorite solution was used as an adjunct to mechanical debridement, and the root canal was filled during the same session [33].
• Systemic distribution of 14C-labeled formaldehyde applied in the root canal following pulpectomy [34].
• Treatment consisted of pulpotomy with calcium hydroxide paste; after 2 1/2 months a permanent root canal filling was placed in the amputated part [35].
• The structure of the coronal, middle and apical parts of root canal walls was examined using transmission electron microscopy [36].

References