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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Signal transduction in the plant immune response.

Complementary biochemical and genetic approaches are being used to dissect the signaling network that regulates the innate immune response in plants. Receptor-mediated recognition of invading pathogens triggers a signal amplification loop that is based on synergistic interactions between nitric oxide, reactive oxygen intermediates and salicylic acid. Alternative resistance mechanisms in Arabidopsis are deployed against different types of pathogens; these mechanisms are mediated by either salicylic acid or the growth regulators jasmonic acid and ethylene.[1]


  1. Signal transduction in the plant immune response. McDowell, J.M., Dangl, J.L. Trends Biochem. Sci. (2000) [Pubmed]
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