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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

SFEMG in ocular myasthenia gravis diagnosis.

BACKGROUND AND OBJECTIVE: In typical cases, the patient's history and clinical examination make it possible to diagnose ocular myasthenia gravis (OMG). But, in many cases a clear clinical picture is not present and OMG diagnosis is very difficult because gold diagnostic standard tests are not available. The diagnostic tests for OMG are usually unable to display a good sensitivity and specificity simultaneously. In this paper, we studied 86 cases submitted for suspected OMG. METHODS: The patients were studied clinically and with various other tests used in OMG diagnosis (SFEMG, repetitive nerve stimulation, Ab anti AChR titration, tensilon test). RESULTS AND CONCLUSION: SFEMG showed the highest sensitivity (100%) while Ab anti AChR showed the highest specificity (100%). To our knowledge this is the largest population of suspected OMG studied using most of the diagnostic parameters, reported in the literature.[1]

References

  1. SFEMG in ocular myasthenia gravis diagnosis. Padua, L., Stalberg, E., LoMonaco, M., Evoli, A., Batocchi, A., Tonali, P. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. (2000) [Pubmed]
 
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