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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Thyroid function in haemodialysed patients of Gassim, Saudi Arabia: TRH stimulation.

To study the hypophysical-pituitary-thyroid axis in Saudi patients on ( RDT), 200 units of TRH were given intravenously predialysis to each of 21 such subjects. As expected (TSH) rose promptly within 30 minutes followed by a gentle decline at 60 minutes. A more gentle rise was also noted in T3 which continued for the 60 minutes of observation. Rather unexpectedly, T4 level was noted to show a reciprocal decline. To our knowledge, this pattern has not been defined in literature. In 12 patients (GH) was noted to rise promptly within 30 minutes followed by a gentle decline at 60 minutes. (LH) and (FSH) did not follow any definite pattern as observed for T3 and T4. Since the oral preparation of TRH is now available, can ( TRH) be effectively used to treat renal dwarfism?[1]

References

  1. Thyroid function in haemodialysed patients of Gassim, Saudi Arabia: TRH stimulation. Soyannwo, M.A., Khandekar, S., Gadallah, M., Muraldhar, K., Abdelrahman, A., Khan, N., Singh, R. African journal of medicine and medical sciences. (1997) [Pubmed]
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