Metabolism and fate of [(14)C]ethametsulfuron-methyl in rutabaga (Brassica napobrassica Mill).
The metabolism and fate of ethametsulfuron-methyl ¿methyl 2-[[[[[4-ethoxy-6-(methylamino)-1,3, 5-triazin-2-yl]amino]carbonyl]amino]sulfonyl]benzoate¿ in rutabaga were investigated. After 72 h, absorption and translocation of [(14)C]ethametsulfuron-methyl in rutabaga did not change for the duration of the study (50 days). Less than 4% of recovered radioactivity was present in the rutabaga root. Ethametsulfuron-methyl was metabolized through a proposed unstable alpha-hydroxy ethoxy intermediate that dissipated 3 days after treatment to two major metabolites, O-desethylethametsulfuron-methyl and N-desmethyl-O-desethylethametsulfuron-methyl, as determined by liquid chromatography-mass spectrometry. It was estimated that at a spray dose of 30 g of active ingredient ha(-)(1) and a harvest weight of 0.5 kg, the edible portion of the rutabaga root would contain no ethametsulfuron-methyl and approximately 1.3 ppb total of both identified metabolites. Residue analysis and toxicological assessment show that ethametsulfuron-methyl and its metabolites should pose little or no risk to consumers of rutabagas.[1]References
- Metabolism and fate of [(14)C]ethametsulfuron-methyl in rutabaga (Brassica napobrassica Mill). Van Eerd, L.L., Hall, J.C. J. Agric. Food Chem. (2000) [Pubmed]
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