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Zhanel, G.G. et al.

Zhanel, Hoban, Karlowsky,

Nitrofurantoin is active against vancomycin-resistant enterococci.

The activity of nitrofurantoin was tested against 300 isolates of Enterococcus faecium, Enterococcus faecalis, and Enterococcus gallinarum. No isolates tested were resistant to nitrofurantoin (MIC, >/=128 microg/ml), including vancomycin-resistant E. faecium isolates with vanA- and vanB-positive genotypes and vancomycin-resistant E. gallinarum isolates. We conclude that nitrofurantoin may provide effective treatment of urinary tract infections caused by vancomycin-resistant enterococci.[1]

References

Nitrofurantoin is active against vancomycin-resistant enterococci. Zhanel, G.G., Hoban, D.J., Karlowsky, J.A. Antimicrob. Agents Chemother. (2001) [Pubmed]

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