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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Urinary Tract

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Disease relevance of Urinary Tract


Psychiatry related information on Urinary Tract


High impact information on Urinary Tract


Chemical compound and disease context of Urinary Tract


Biological context of Urinary Tract


Anatomical context of Urinary Tract


Associations of Urinary Tract with chemical compounds


Gene context of Urinary Tract

  • Importantly, generation of THP-specific Abs consistently detectable in urinary tract inflammation was completely blunted in Tlr4-/- mice [35].
  • CONCLUSION: Pending large prospective studies, the extension of the current surveillance program in MSH2 mutation carriers with the inclusion of the urinary tract should be considered [36].
  • An understanding of how FGF-10 works in conjunction with these other processes will lead to better management of many diseases of the bladder and urinary tract [37].
  • Our results suggest that FGFR3 antagonists could be developed as possible therapeutics for treatment of urinary tract carcinoma [38].
  • Though an immune infiltrate was present occasionally in transgenic skin, the infiltrate was not the primary cause of the epithelial hyperproliferation, as the immune reaction was not observed in all affected transgenics, and the transgene induced identical skin and urinary tract abnormalities in immunodeficient Rag1-null mice [39].

Analytical, diagnostic and therapeutic context of Urinary Tract


  1. Widespread distribution of urinary tract infections caused by a multidrug-resistant Escherichia coli clonal group. Manges, A.R., Johnson, J.R., Foxman, B., O'Bryan, T.T., Fullerton, K.E., Riley, L.W. N. Engl. J. Med. (2001) [Pubmed]
  2. Folic acid antagonists during pregnancy and the risk of birth defects. Hernández-Díaz, S., Werler, M.M., Walker, A.M., Mitchell, A.A. N. Engl. J. Med. (2000) [Pubmed]
  3. The locus for Meckel syndrome with multiple congenital anomalies maps to chromosome 17q21-q24. Paavola, P., Salonen, R., Weissenbach, J., Peltonen, L. Nat. Genet. (1995) [Pubmed]
  4. Acquired circulating anticoagulant to factor VIII. Response to high doses of cryoprecipitate and immunosuppressive therapy. Vera, J.C., Herzig, E.G., Sise, H.S., Brauer, M.J. JAMA (1975) [Pubmed]
  5. Monocytes and polymorphonuclear neutrophils of patients with streptococcal pharyngitis express increased numbers of type I IgG Fc receptors. Guyre, P.M., Campbell, A.S., Kniffin, W.D., Fanger, M.W. J. Clin. Invest. (1990) [Pubmed]
  6. Urinary urgency and frequency, and chronic urethral and/or pelvic pain in females. Can doxycycline help? Burkhard, F.C., Blick, N., Hochreiter, W.W., Studer, U.E. J. Urol. (2004) [Pubmed]
  7. Overview. New standards for UTI--1988. Parsons, C.L. Urology (1988) [Pubmed]
  8. Mitochondrial DNA mutations in a patient with sex reversal and clinical features consistent with Fraser syndrome. Wong, L.J., Lin, Y.H., Suwannarat, P., Hsu, C.H., Kwon, H.Y., Mackowiak, S. Clin. Genet. (2005) [Pubmed]
  9. Incidence, risk factors, and outcomes of fecal incontinence after acute brain injury: findings from the Traumatic Brain Injury Model Systems national database. Foxx-Orenstein, A., Kolakowsky-Hayner, S., Marwitz, J.H., Cifu, D.X., Dunbar, A., Englander, J., Francisco, G. Archives of physical medicine and rehabilitation. (2003) [Pubmed]
  10. Trimethoprim alone in the treatment of urinary tract infections: eight years of experience in Finland. Kasanen, A., Sundquist, H. Rev. Infect. Dis. (1982) [Pubmed]
  11. A controlled trial of intravaginal estriol in postmenopausal women with recurrent urinary tract infections. Raz, R., Stamm, W.E. N. Engl. J. Med. (1993) [Pubmed]
  12. Association of the Lewis blood-group phenotype with recurrent urinary tract infections in women. Sheinfeld, J., Schaeffer, A.J., Cordon-Cardo, C., Rogatko, A., Fair, W.R. N. Engl. J. Med. (1989) [Pubmed]
  13. A randomized double-blind study of acetohydroxamic acid in struvite nephrolithiasis. Williams, J.J., Rodman, J.S., Peterson, C.M. N. Engl. J. Med. (1984) [Pubmed]
  14. Efficacy of single-dose and conventional amoxicillin therapy in urinary-tract infection localized by the antibody-coated bacteria technic. Fang, L.S., Tolkoff-Rubin, N.E., Rubin, R.H. N. Engl. J. Med. (1978) [Pubmed]
  15. Saturation-inhibition index as a measure of the risk of calcium oxalate stone formation in the urinary tract. Robertson, W.G., Peacock, M., Marshall, R.W., Marshall, D.H., Nordin, B.E. N. Engl. J. Med. (1976) [Pubmed]
  16. Epithelial secretion of C3 promotes colonization of the upper urinary tract by Escherichia coli. Springall, T., Sheerin, N.S., Abe, K., Holers, V.M., Wan, H., Sacks, S.H. Nat. Med. (2001) [Pubmed]
  17. Treatable complications in undiagnosed cases of autosomal dominant polycystic kidney disease. Ravine, D., Walker, R.G., Gibson, R.N., Sheffield, L.J., Kincaid-Smith, P., Danks, D.M. Lancet (1991) [Pubmed]
  18. The renin angiotensin system and kidney development. Matsusaka, T., Miyazaki, Y., Ichikawa, I. Annu. Rev. Physiol. (2002) [Pubmed]
  19. Risk factors for nephrotoxicity in patients treated with aminoglycosides. Moore, R.D., Smith, C.R., Lipsky, J.J., Mellits, E.D., Lietman, P.S. Ann. Intern. Med. (1984) [Pubmed]
  20. Autosomal recessive Wolfram syndrome associated with an 8.5-kb mtDNA single deletion. Barrientos, A., Casademont, J., Saiz, A., Cardellach, F., Volpini, V., Solans, A., Tolosa, E., Urbano-Marquez, A., Estivill, X., Nunes, V. Am. J. Hum. Genet. (1996) [Pubmed]
  21. Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter. Miyazaki, Y., Oshima, K., Fogo, A., Hogan, B.L., Ichikawa, I. J. Clin. Invest. (2000) [Pubmed]
  22. Uroplakin IIIb, a urothelial differentiation marker, dimerizes with uroplakin Ib as an early step of urothelial plaque assembly. Deng, F.M., Liang, F.X., Tu, L., Resing, K.A., Hu, P., Supino, M., Hu, C.C., Zhou, G., Ding, M., Kreibich, G., Sun, T.T. J. Cell Biol. (2002) [Pubmed]
  23. Virulence factors in Escherichia coli urinary tract infection. Johnson, J.R. Clin. Microbiol. Rev. (1991) [Pubmed]
  24. Expression of platelet-derived endothelial cell growth factor and its potential role in up-regulation of angiogenesis in scarred kidneys secondary to urinary tract diseases. Konda, R., Sato, H., Sakai, K., Sato, M., Orikasa, S., Kimura, N. Am. J. Pathol. (1999) [Pubmed]
  25. Failure of elastic fiber homeostasis leads to pelvic floor disorders. Liu, X., Zhao, Y., Pawlyk, B., Damaser, M., Li, T. Am. J. Pathol. (2006) [Pubmed]
  26. Maternal cocaine use during early pregnancy as a risk factor for congenital urogenital anomalies. Chávez, G.F., Mulinare, J., Cordero, J.F. JAMA (1989) [Pubmed]
  27. Interleukin-8 and the neutrophil response to mucosal gram-negative infection. Agace, W.W., Hedges, S.R., Ceska, M., Svanborg, C. J. Clin. Invest. (1993) [Pubmed]
  28. Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery. Chang, C.P., McDill, B.W., Neilson, J.R., Joist, H.E., Epstein, J.A., Crabtree, G.R., Chen, F. J. Clin. Invest. (2004) [Pubmed]
  29. Relation between endemic (Balkan) nephropathy and urinary-tract tumours. Sattler, T.A., Dimitrov, T., Hall, P.W. Lancet (1977) [Pubmed]
  30. E-cadherin promotes intraepithelial expansion of bladder carcinoma cells in an in vitro model of carcinoma in situ. Bindels, E.M., Vermey, M., van den Beemd, R., Dinjens, W.N., Van Der Kwast, T.H. Cancer Res. (2000) [Pubmed]
  31. Urinary-tract stones resulting from the excretion of oxypurinol. Landgrebe, A.R., Nyhan, W.L., Coleman, M. N. Engl. J. Med. (1975) [Pubmed]
  32. Pharmacology of the lower urinary tract. de Groat, W.C., Yoshimura, N. Annu. Rev. Pharmacol. Toxicol. (2001) [Pubmed]
  33. Trimethoprim therapy for urinary tract infection. Long-term prophylaxis in a uremic patient. Kunin, C.M., Craig, W.A., Uehling, D.T. JAMA (1978) [Pubmed]
  34. Postcoital antimicrobial prophylaxis for recurrent urinary tract infection. A randomized, double-blind, placebo-controlled trial. Stapleton, A., Latham, R.H., Johnson, C., Stamm, W.E. JAMA (1990) [Pubmed]
  35. Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism. Säemann, M.D., Weichhart, T., Zeyda, M., Staffler, G., Schunn, M., Stuhlmeier, K.M., Sobanov, Y., Stulnig, T.M., Akira, S., von Gabain, A., von Ahsen, U., Hörl, W.H., Zlabinger, G.J. J. Clin. Invest. (2005) [Pubmed]
  36. MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: a study of hereditary nonpolyposis colorectal cancer families. Vasen, H.F., Stormorken, A., Menko, F.H., Nagengast, F.M., Kleibeuker, J.H., Griffioen, G., Taal, B.G., Moller, P., Wijnen, J.T. J. Clin. Oncol. (2001) [Pubmed]
  37. Fibroblast growth factor-10 is a mitogen for urothelial cells. Bagai, S., Rubio, E., Cheng, J.F., Sweet, R., Thomas, R., Fuchs, E., Grady, R., Mitchell, M., Bassuk, J.A. J. Biol. Chem. (2002) [Pubmed]
  38. Fibroblast growth factor receptor 3 is overexpressed in urinary tract carcinomas and modulates the neoplastic cell growth. Gómez-Román, J.J., Saenz, P., Molina, M., Cuevas González, J., Escuredo, K., Santa Cruz, S., Junquera, C., Simón, L., Martínez, A., Gutiérrez Baños, J.L., López-Brea, M., Esparza, C., Val-Bernal, J.F. Clin. Cancer Res. (2005) [Pubmed]
  39. Ectopic expression of the nude gene induces hyperproliferation and defects in differentiation: implications for the self-renewal of cutaneous epithelia. Prowse, D.M., Lee, D., Weiner, L., Jiang, N., Magro, C.M., Baden, H.P., Brissette, J.L. Dev. Biol. (1999) [Pubmed]
  40. Epidemiologic study of abuse of analgesics containing phenacetin. Renal morbidity and mortality (1968-1979). Dubach, U.C., Rosner, B., Pfister, E. N. Engl. J. Med. (1983) [Pubmed]
  41. Diagnosis of genito-urinary tract cancer by detection of minichromosome maintenance 5 protein in urine sediments. Stoeber, K., Swinn, R., Prevost, A.T., de Clive-Lowe, P., Halsall, I., Dilworth, S.M., Marr, J., Turner, W.H., Bullock, N., Doble, A., Hales, C.N., Williams, G.H. J. Natl. Cancer Inst. (2002) [Pubmed]
  42. Adjuvant chemotherapy with paclitaxel and carboplatin in patients with advanced carcinoma of the upper urinary tract: a study by the Hellenic Cooperative Oncology Group. Bamias, A., Deliveliotis, C.h., Fountzilas, G., Gika, D., Anagnostopoulos, A., Zorzou, M.P., Kastritis, E., Constantinides, C., Kosmidis, P., Dimopoulos, M.A. J. Clin. Oncol. (2004) [Pubmed]
  43. Cisplatin, methotrexate, and vinblastine (CMV): an effective chemotherapy regimen for metastatic transitional cell carcinoma of the urinary tract. A Northern California Oncology Group study. Harker, W.G., Meyers, F.J., Freiha, F.S., Palmer, J.M., Shortliffe, L.D., Hannigan, J.F., McWhirter, K.M., Torti, F.M. J. Clin. Oncol. (1985) [Pubmed]
  44. Tumorigenicity of sodium ascorbate in male rats. Cohen, S.M., Anderson, T.A., de Oliveira, L.M., Arnold, L.L. Cancer Res. (1998) [Pubmed]
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