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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Chronic nervous-system effects of long-term occupational exposure to DDT.

Dichlorodiphenyltrichloroethane (DDT) is a compound with moderate toxicity that is judged to be safe for occupational use, although little is known about its long-term effects on the human nervous system. We investigated chronic nervous-system effects of long-term occupational exposure to DDT by comparing the neurobehavioural performance of retired malaria-control workers with a reference group of retired guards and drivers. DDT-exposed workers did worse on tests assessing various neurobehavioural functions than controls; performance significantly deteriorated with increasing years of DDT application. Our results could not be explained by exposure to cholinesterase-inhibiting pesticides or other potential confounding factors.[1]

References

  1. Chronic nervous-system effects of long-term occupational exposure to DDT. van Wendel de Joode, B., Wesseling, C., Kromhout, H., Monge, P., García, M., Mergler, D. Lancet (2001) [Pubmed]
 
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