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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Occupational Exposure

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Disease relevance of Occupational Exposure


Psychiatry related information on Occupational Exposure


High impact information on Occupational Exposure


Chemical compound and disease context of Occupational Exposure


Biological context of Occupational Exposure


Anatomical context of Occupational Exposure


Associations of Occupational Exposure with chemical compounds

  • PURPOSE: The objective of this study was to determine the prevalence and time of appearance of serum anti-p53 antibodies during the pathogenesis of ASL associated with occupational exposure to vinyl chloride [31].
  • Increased risks of NHL were also observed among those with occupational exposure to organochlorine insecticides, such as DDT [1.82 (1.04-3.2)] and organic solvents [1.35 (1.06-1.7)], and to other chemicals typically encountered in the agricultural, forestry, or wood products industries [32].
  • These data support the conclusion that occupational exposure to o-toluidine is the most likely causal agent of the bladder cancer excess observed among workers in the rubber chemicals department of the plant under study, although exposures to aniline and 4-ABP cannot be ruled out [33].
  • Glucose tolerance and occupational exposure to carbon disulphide [34].
  • Thus, in a collaborative European study, we assessed the renal effects of occupational exposure to perchloroethylene (PCE) in dry-cleaners compared with matched controls who were simultaneously examined [35].

Gene context of Occupational Exposure


Analytical, diagnostic and therapeutic context of Occupational Exposure


  1. Zidovudine after occupational exposure to the human immunodeficiency virus. Rhame, F.S., Russell, A.L. N. Engl. J. Med. (1991) [Pubmed]
  2. Ectopic pregnancy and occupational exposure to antineoplastic drugs. Saurel-Cubizolles, M.J., Job-Spira, N., Estryn-Behar, M. Lancet (1993) [Pubmed]
  3. Fulminant hepatic failure after occupational exposure to 2-nitropropane. Harrison, R., Letz, G., Pasternak, G., Blanc, P. Ann. Intern. Med. (1987) [Pubmed]
  4. Liver disease associated with occupational exposure to the solvent dimethylformamide. Redlich, C.A., Beckett, W.S., Sparer, J., Barwick, K.W., Riely, C.A., Miller, H., Sigal, S.L., Shalat, S.L., Cullen, M.R. Ann. Intern. Med. (1988) [Pubmed]
  5. Seizures and dermatitis after exposure to caprolactam. Tuma, S.N., Orson, F., Fossella, F.V., Waidhofer, W. Arch. Intern. Med. (1981) [Pubmed]
  6. Occupational exposures to solvents and aluminium and estimated risk of Alzheimer's disease. Graves, A.B., Rosner, D., Echeverria, D., Mortimer, J.A., Larson, E.B. Occupational and environmental medicine. (1998) [Pubmed]
  7. The effect of combined exposures to ethanol and xylene on rat hepatic microsomal monooxygenase activities. Wiśniewska-Knypl, J.M., Wrońska-Nofer, T., Jajte, J., Jedlińska, U. Alcohol (1989) [Pubmed]
  8. Toxicology of n-pentane (CAS no. 109-66-0). McKee, R., Frank, E., Heath, J., Owen, D., Przygoda, R., Trimmer, G., Whitman, F. Journal of applied toxicology : JAT. (1998) [Pubmed]
  9. Epstein-Barr virus infection, salted fish and nasopharyngeal carcinoma. A case-control study in southern China. Zheng, X., Yan, L., Nilsson, B., Eklund, G., Drettner, B. Acta oncologica (Stockholm, Sweden) (1994) [Pubmed]
  10. Choice reaction time in workers exposed to styrene vapour. Mackay, C.J., Kelman, G.R. Human toxicology. (1986) [Pubmed]
  11. Latex glove allergy. A survey of the US Army Dental Corps. Berky, Z.T., Luciano, W.J., James, W.D. JAMA (1992) [Pubmed]
  12. Epidemiologic support for ethylene oxide as a cancer-causing agent. Hogstedt, C., Aringer, L., Gustavsson, A. JAMA (1986) [Pubmed]
  13. 2,3,7,8-Tetrachlorodibenzo-p-dioxin levels in adipose tissue of exposed and control persons in Missouri. An interim report. Patterson, D.G., Hoffman, R.E., Needham, L.L., Roberts, D.W., Bagby, J.R., Pirkle, J.L., Falk, H., Sampson, E.J., Houk, V.N. JAMA (1986) [Pubmed]
  14. Two fatalities after acute occupational exposure to ethylene dibromide. Letz, G.A., Pond, S.M., Osterloh, J.D., Wade, R.L., Becker, C.E. JAMA (1984) [Pubmed]
  15. Occupational exposure to hexachlorocyclopentadiene. How safe is sewage? Morse, D.L., Kominsky, J.R., Wisseman, C.L., Landrigan, P.J. JAMA (1979) [Pubmed]
  16. Occupational exposures to metals as risk factors for Parkinson's disease. Gorell, J.M., Johnson, C.C., Rybicki, B.A., Peterson, E.L., Kortsha, G.X., Brown, G.G., Richardson, R.J. Neurology (1997) [Pubmed]
  17. Hypersensitivity pneumonitis (extrinsic allergic alveolitis) induced by isocyanates. Baur, X. J. Allergy Clin. Immunol. (1995) [Pubmed]
  18. Risk factors for meningioma in adults: a case-control study in northeast China. Hu, J., Little, J., Xu, T., Zhao, X., Guo, L., Jia, X., Huang, G., Bi, D., Liu, R. Int. J. Cancer (1999) [Pubmed]
  19. Liver angiosarcoma and hemangiopericytoma after occupational exposure to vinyl chloride monomer. Hozo, I., Miric, D., Bojic, L., Giunio, L., Lusic, I., Culic, V., Simunic, M. Environ. Health Perspect. (2000) [Pubmed]
  20. Paternal occupational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and birth outcomes of offspring: birth weight, preterm delivery, and birth defects. Lawson, C.C., Schnorr, T.M., Whelan, E.A., Deddens, J.A., Dankovic, D.A., Piacitelli, L.A., Sweeney, M.H., Connally, L.B. Environ. Health Perspect. (2004) [Pubmed]
  21. Effects of arsenic exposure among semiconductor workers: a cautionary note on urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine. Hu, C.W., Pan, C.H., Huang, Y.L., Wu, M.T., Chang, L.W., Wang, C.J., Chao, M.R. Free Radic. Biol. Med. (2006) [Pubmed]
  22. Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations. Nan, H.M., Kim, H., Lim, H.S., Choi, J.K., Kawamoto, T., Kang, J.W., Lee, C.H., Kim, Y.D., Kwon, E.H. Carcinogenesis (2001) [Pubmed]
  23. Clinical pharmacokinetics of metronidazole and other nitroimidazole anti-infectives. Lau, A.H., Lam, N.P., Piscitelli, S.C., Wilkes, L., Danziger, L.H. Clinical pharmacokinetics. (1992) [Pubmed]
  24. Occupational exposure to organic solvents and K-ras mutations in exocrine pancreatic cancer. Alguacil, J., Porta, M., Malats, N., Kauppinen, T., Kogevinas, M., Benavides, F.G., Partanen, T., Carrato, A. Carcinogenesis (2002) [Pubmed]
  25. Variation of the N-acetyltransferase 2 gene in a Romanian and a Kyrgyz population. Rabstein, S., Unfried, K., Ranft, U., Illig, T., Kolz, M., Rihs, H.P., Mambetova, C., Vlad, M., Brüning, T., Pesch, B. Cancer Epidemiol. Biomarkers Prev. (2006) [Pubmed]
  26. First analysis of cancer incidence and occupational radiation exposure based on the National Dose Registry of Canada. Sont, W.N., Zielinski, J.M., Ashmore, J.P., Jiang, H., Krewski, D., Fair, M.E., Band, P.R., Létourneau, E.G. Am. J. Epidemiol. (2001) [Pubmed]
  27. Human cytogenetic biomonitoring of occupational exposure to 1,3-butadiene. Sorsa, M., Autio, K., Demopoulos, N.A., Järventaus, H., Rössner, P., Srám, R.J., Stephanou, G., Vlachodimitropoulos, D. Mutat. Res. (1994) [Pubmed]
  28. Heterogeneous effect of an Emergency Department Expert Charting System. Buller-Close, K., Schriger, D.L., Baraff, L.J. Annals of emergency medicine. (2003) [Pubmed]
  29. The influence of occupational exposure to PAHs on the blood plasma levels of p53 and p21WAF1 proteins. Rössner, P., Binková, B., Srám, R.J. Mutat. Res. (2003) [Pubmed]
  30. Hepatic damage after exposure to halothane in medical personnel. Neuberger, J., Vergani, D., Mieli-Vergani, G., Davis, M., Williams, R. British journal of anaesthesia. (1981) [Pubmed]
  31. Anti-p53 antibodies in sera of workers occupationally exposed to vinyl chloride. Trivers, G.E., Cawley, H.L., DeBenedetti, V.M., Hollstein, M., Marion, M.J., Bennett, W.P., Hoover, M.L., Prives, C.C., Tamburro, C.C., Harris, C.C. J. Natl. Cancer Inst. (1995) [Pubmed]
  32. Soft tissue sarcoma and non-Hodgkin's lymphoma in relation to phenoxyherbicide and chlorinated phenol exposure in western Washington. Woods, J.S., Polissar, L., Severson, R.K., Heuser, L.S., Kulander, B.G. J. Natl. Cancer Inst. (1987) [Pubmed]
  33. Monitoring of aromatic amine exposures in workers at a chemical plant with a known bladder cancer excess. Ward, E.M., Sabbioni, G., DeBord, D.G., Teass, A.W., Brown, K.K., Talaska, G.G., Roberts, D.R., Ruder, A.M., Streicher, R.P. J. Natl. Cancer Inst. (1996) [Pubmed]
  34. Glucose tolerance and occupational exposure to carbon disulphide. Kujalová, V., Lukás, E., Sperlingová, I., Frantík, E. Lancet (1979) [Pubmed]
  35. Nephropathies and exposure to perchloroethylene in dry-cleaners. Mutti, A., Alinovi, R., Bergamaschi, E., Biagini, C., Cavazzini, S., Franchini, I., Lauwerys, R.R., Bernard, A.M., Roels, H., Gelpi, E. Lancet (1992) [Pubmed]
  36. GST, NAT, SULT1A1, CYP1B1 genetic polymorphisms, interactions with environmental exposures and bladder cancer risk in a high-risk population. Hung, R.J., Boffetta, P., Brennan, P., Malaveille, C., Hautefeuille, A., Donato, F., Gelatti, U., Spaliviero, M., Placidi, D., Carta, A., Scotto di Carlo, A., Porru, S. Int. J. Cancer (2004) [Pubmed]
  37. Associations of blood pressure and hypertension with lead dose measures and polymorphisms in the vitamin D receptor and delta-aminolevulinic acid dehydratase genes. Lee, B.K., Lee, G.S., Stewart, W.F., Ahn, K.D., Simon, D., Kelsey, K.T., Todd, A.C., Schwartz, B.S. Environ. Health Perspect. (2001) [Pubmed]
  38. gamma-Glutamyltransferase isoenzyme pattern in workers exposed to tetrachloroethylene. Gennari, P., Naldi, M., Motta, R., Nucci, M.C., Giacomini, C., Violante, F.S., Raffi, G.B. Am. J. Ind. Med. (1992) [Pubmed]
  39. Altered mRNA expression of the Rb and p16 tumor suppressor genes and of CDK4 in transitional cell carcinomas of the urinary bladder associated with tumor progression. Quentin, T., Henke, C., Korabiowska, M., Schlott, T., Zimmerman, B., Kunze, E. Anticancer Res. (2004) [Pubmed]
  40. Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes. Thier, R., Brüning, T., Roos, P.H., Rihs, H.P., Golka, K., Ko, Y., Bolt, H.M. International journal of hygiene and environmental health. (2003) [Pubmed]
  41. Salmonella typhimurium strains expressing human arylamine N-acetyltransferases: metabolism and mutagenic activation of aromatic amines. Grant, D.M., Josephy, P.D., Lord, H.L., Morrison, L.D. Cancer Res. (1992) [Pubmed]
  42. Cost-effectiveness of chemoprophylaxis after occupational exposure to HIV. Pinkerton, S.D., Holtgrave, D.R., Pinkerton, H.J. Arch. Intern. Med. (1997) [Pubmed]
  43. Urothelial cell DNA adducts in rubber workers. Vermeulen, R., Talaska, G., Schumann, B., Bos, R.P., Rothman, N., Kromhout, H. Environ. Mol. Mutagen. (2002) [Pubmed]
  44. Tuberculosis infection among staff at a Canadian community hospital. Liss, G.M., Khan, R., Koven, E., Simor, A.E. Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America. (1996) [Pubmed]
  45. Occupational exposure to desflurane and isoflurane during cardiopulmonary bypass: is the gas outlet of the membrane oxygenator an operating theatre pollution hazard? Hoerauf, K., Harth, M., Wild, K., Hobbhahn, J. British journal of anaesthesia. (1997) [Pubmed]
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