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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

The Brix domain protein family -- a key to the ribosomal biogenesis pathway?

Six (one archaean and five eukaryotic) protein families have similar domain architecture that includes a central globular Brix domain, and optional N- and obligatory C-terminal segments, both with charged low-complexity regions. Biological data for some proteins in this superfamily suggest a role in ribosome biogenesis and rRNA binding.[1]

References

  1. The Brix domain protein family -- a key to the ribosomal biogenesis pathway? Eisenhaber, F., Wechselberger, C., Kreil, G. Trends Biochem. Sci. (2001) [Pubmed]
 
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