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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Cross-sectional pattern of collateral vessels in patients with superficial femoral artery occlusion.

RATIONALE AND OBJECTIVES: The purpose of this study was to identify the cross-sectional location of collateral vessels in patients with peripheral vascular disease on three-dimensional magnetic resonance angiograms (3D MRAs) to suggest sites for intravascular or transcutaneous angiogenesis gene delivery in the lower extremity. METHODS: The axial locations were measured and categorized by tissue compartments, as well as by radial coordinates with respect to the femur. RESULTS: Collateral vessels in the thigh were identified in 24 of 93 consecutive patients who underwent peripheral 3D MRA. Ninety-one percent (99/109) of the observed collaterals were located near the adductor canal level of the thigh, with 78% (31/46) of these collaterals located in the fat in or surrounding the posterior muscle. CONCLUSIONS: The majority of collateral vessels in the thigh are located in the fat or muscle within the posterior compartment near the femur at the level of the adductor canal.[1]

References

  1. Cross-sectional pattern of collateral vessels in patients with superficial femoral artery occlusion. Wecksell, M.B., Winchester, P.A., Bush, H.L., Kent, K.C., Prince, M.R., Wang, Y. Investigative radiology. (2001) [Pubmed]
 
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