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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Mapping out the roles of MAP kinases in plant defense.

Arabidopsis contains 20 MAP kinase genes, but their roles in plant physiology have remained largely unknown because of a lack of mutants. Recent papers from two groups have shed new light on the function of two different MAP kinases. The Arabidopsis MPK4 gene appears to negatively regulate salicylic acid-mediated defense responses and positively regulate jasmonic acid-induced responses. The tobacco SIPK gene (orthologous to Arabidopsis MPK6) appears to positively regulate programmed cell death.[1]


  1. Mapping out the roles of MAP kinases in plant defense. Innes, R.W. Trends Plant Sci. (2001) [Pubmed]
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