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Ramsey, P.S. et al.

Ramsey, Rouse,

Magnesium sulfate as a tocolytic agent.

Although magnesium sulfate is widely used as a tocolytic agent in the hope of preventing spontaneous preterm birth, there is a paucity of data from large well-designed randomized clinical studies demonstrating the efficacy of magnesium sulfate therapy. Given the potential for untoward side effects and the inherent risks of magnesium sulfate therapy, a thorough understanding of the potential risks and benefits of this agent is needed. To accomplish this understanding we have provided a detailed review the history, pharmacology, physiology, maternal/fetal side effects, and tocolytic efficacy of magnesium sulfate.[1]

References

Magnesium sulfate as a tocolytic agent. Ramsey, P.S., Rouse, D.J. Semin. Perinatol. (2001) [Pubmed]

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