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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Metabolism of methocarbamol (robaxin) in the isolated perfused rat liver and identification of glucuronides.

1. Permethylation and g.l.c.-mass spectrometric analysis of bile from an isolated rat liver perfusion to which methocarmol was added showed seven components not present in control bile: methocarbamol, glucuronides of methocarbamol and desmethyl-methocarbamol, and four glucuronides of hydroxylated methocarbamol metabolites. 2. An interesting rearrangement of a methyl group has been found in the mass spectrum of 3-(2-methoxyphenyloxy)-1,2-dimethoxypropane, the permethylation product from methocarbamol.[1]

References

  1. Metabolism of methocarbamol (robaxin) in the isolated perfused rat liver and identification of glucuronides. Thompson, R.M., Gerber, N., Seibert, R.A. Xenobiotica (1975) [Pubmed]
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