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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Thymosin alpha1 inhibits mammary carcinogenesis in Fisher rats.

The effects of thymosin alpha1 (Talpha1) on mammary carcinogenesis was investigated in Fisher rats. Mammary carcinomas were observed 3 months after N-nitrosomethylurea (NMU) injection (10mg, i.p.) into Fisher rats. Daily administration of Talpha1 (10 microg, s.c.) reduced mammary carcinoma incidence and prolonged survival time. Animals treated with exogenous Talpha1 had a significantly greater blood white cell density than control Fisher rats. These results suggest that Talpha1 prevents mammary carcinoma incidence as a result of stimulation of the immune system.[1]

References

  1. Thymosin alpha1 inhibits mammary carcinogenesis in Fisher rats. Moody, T.W., Tuthill, C., Badamchian, M., Goldstein, A.L. Peptides (2002) [Pubmed]
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