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Bannister, A.J. et al.

Histone methylation: dynamic or static?

Methylation of histones mediates transcriptional silencing at heterochromatin sites and affects regulated transcription at euchromatic loci. So is the methyl group a permanent mark on histones, or can it be removed by an active process necessary for regulated gene expression?[1]

References

Histone methylation: dynamic or static? Bannister, A.J., Schneider, R., Kouzarides, T. Cell (2002) [Pubmed]

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