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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Healing of fresh tibial fractures with OP-1. A preliminary report.

Osteogenic proteins (OP) are elements of a class of natural growth factors called Bone Morphogenetic Proteins (BMP). A specific member of this class is OP-1, a human recombinant protein that has osteogenic properties. The osteoinductive and osteoconductive properties of OP-1, with its specific collagen matrix, promote the generation of new functionally active, biologically and biomechanically mature bone. We carried out a clinical study to verify the potential of this protein in fresh tibial closed fractures, using OP-1 associated with osteosynthesis by means of a monolateral external fixator.[1]

References

  1. Healing of fresh tibial fractures with OP-1. A preliminary report. Maniscalco, P., Gambera, D., Bertone, C., Rivera, F., Crainz, E., Urgelli, S. Acta bio-medica de L'Ateneo parmense : organo della Società di medicina e scienze naturali di Parma. (2002) [Pubmed]
 
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