The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

A new P-glycoprotein inhibitor from the caper spurge (Euphorbia lathyris).

The macrocyclic lathyrane polyester Euphorbia factor L10 (1a) has been obtained from the seeds of the caper spurge (E. lathyris). The interaction of L10 (1a) and its acetyl derivative (1b) with P-glycoprotein, a multidrug transporter overexpressed in cancer cells and responsible for resistance to chemotherapy, was investigated. The results established lathyrane diterpenoids as a novel chemotype for P-glycoprotein inhibitors.[1]

References

  1. A new P-glycoprotein inhibitor from the caper spurge (Euphorbia lathyris). Appendino, G., Della Porta, C., Conseil, G., Sterner, O., Mercalli, E., Dumontet, C., Di Pietro, A. J. Nat. Prod. (2003) [Pubmed]
 
WikiGenes - Universities