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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Converting the sacrificial DNA repair protein N-ada into a catalytic methyl phosphotriester repair enzyme.

Mutation of the active-site residue Cys38 of N-Ada converts it from a sacrificial DNA repair protein to an enzyme that uses methanethiol as an external sacrificial reagent to repair DNA methyl phosphotriesters catalytically.[1]

References

  1. Converting the sacrificial DNA repair protein N-ada into a catalytic methyl phosphotriester repair enzyme. He, C., Wei, H., Verdine, G.L. J. Am. Chem. Soc. (2003) [Pubmed]
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