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Tuxworth, R. et al.

Asymmetric cell division: Miranda chauffeured by Jaguar?

Drosophila neuroblasts divide to produce daughters of distinct fate by asymmetrically localizing cell fate determinants and segregating them preferentially to one daughter. An intact F-actin cytoskeleton was known to be required, and now a myosin VI (Jaguar) has been shown to be necessary for basal targeting of cell fate determinants in neuroblasts.[1]

References

Asymmetric cell division: Miranda chauffeured by Jaguar? Tuxworth, R., Chia, W. Mol. Cell (2003) [Pubmed]

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