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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Hypersomnia associated with bilateral posterior hypothalamic lesion. A polysomnographic case study.

We examined an obese 58-year-old patient with a bilateral posterior hypothalamic lesion of unknown etiology. A 24-hour polysomnography revealed a markedly increased total sleep time (17.6 h). During daytime, only 3 continuous wake phases occurred. REM periods occurred only between 5 p.m. and 6 a.m. We conclude from our results that, similar to the results from animal experiments, the posterior hypothalamus in humans plays a critical role in the maintenance of wakefulness.[1]

References

  1. Hypersomnia associated with bilateral posterior hypothalamic lesion. A polysomnographic case study. Eisensehr, I., Noachtar, S., von Schlippenbach, C., Uttner, I., Kleine, J., Seelos, K., Helmchen, C. Eur. Neurol. (2003) [Pubmed]
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