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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Effect of interstimulus interval on attentional modulation of cortical activities in human somatosensory areas.

OBJECTIVE: To investigate the effect of interstimulus interval (ISI) on attentional enhancement of cortical activity in human somatosensory cortices. METHODS: Somatosensory magnetic fields (SEFs) evoked by electrical stimulation of the right median nerve at ISIs of 0.5, 1, 3 and 5 s were recorded in two separate conditions by using whole head type magnetoencephalography. In the attend-condition: subjects directed attention to the stimuli by watching the stimulated body site and mentally counting the stimuli. In the ignore-condition: subjects ignored the stimuli by reading a book. RESULTS: Attention to the tactile stimulation amplified SEFs in contralateral secondary (SIT) at ISIs of 1, 3 and 5 s and in ipsilateral SII at ISI of 5 s. There was no effect of attention on the SEF in primary. The ratios of the equivalent current dipole moments calculated for the attend-condition compared to ignore-condition were 1.49 +/- 0.14 at ISI of 1 s, 1.47 +/- 0.29 at 3 s and 1.34 +/- 0.23 at 5 s in the contralateral SII and 1.40 +/- 0.24 at 5 s in the ipsilateral SII. CONCLUSIONS: Time longer than 0.5 s might be required for active attention genesis and, after it was generated, the cortical activation in the attend condition was proportional to the activity in the ignore condition.[1]

References

  1. Effect of interstimulus interval on attentional modulation of cortical activities in human somatosensory areas. Hamada, Y., Okita, H., Suzuki, R. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. (2003) [Pubmed]
 
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