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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

The efficacy of permethrin-treated bed nets on child mortality and morbidity in western Kenya II. Study design and methods.

This paper describes the study design and methods used in a large community-based, group-randomized, controlled trial of permethrin-treated bed nets (ITNs) in an area with intense, perennial malaria transmission in western Kenya conducted between 1996 and 1999. A multi-disciplinary framework was used to explore the efficacy of ITNs in the reduction of all-cause mortality in children less than five years old, the clinical, entomologic, immunologic, and economic impact of ITNs, the social and behavioral determinants of ITN use, and the use of a geographic information system to allow for spatial analyses of these outcomes. Methodologic difficulties encountered in such large-scale field trials are discussed.[1]

References

  1. The efficacy of permethrin-treated bed nets on child mortality and morbidity in western Kenya II. Study design and methods. Phillips-Howard, P.A., ter Kuile, F.O., Nahlen, B.L., Alaii, J.A., Gimnig, J.E., Kolczak, M.S., Terlouw, D.J., Kariuki, S.K., Shi, Y.P., Kachur, S.P., Hightower, A.W., Vulule, J.M., Hawley, W.A. Am. J. Trop. Med. Hyg. (2003) [Pubmed]
 
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