- TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes. Souza, S.C., Palmer, H.J., Kang, Y.H., Yamamoto, M.T., Muliro, K.V., Paulson, K.E., Greenberg, A.S. J. Cell. Biochem. (2003)