Gene Review:
Plin1 - perilipin 1
Mus musculus
Synonyms:
6030432J05Rik, Lipid droplet-associated protein, Peri, Perilipin A, Perilipin-1, ...
- Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice. Martinez-Botas, J., Anderson, J.B., Tessier, D., Lapillonne, A., Chang, B.H., Quast, M.J., Gorenstein, D., Chen, K.H., Chan, L. Nat. Genet. (2000)
- Evaluation of chemopreventive action of Ginsenoside Rp1. Kumar, A., Kumar, M., Panwar, M., Samarth, R.M., Park, T.Y., Park, M.H., Kimura, H. Biofactors (2006)
- Distinct roles of vascular endothelial growth factor-d in lymphangiogenesis and metastasis. Kopfstein, L., Veikkola, T., Djonov, V.G., Baeriswyl, V., Schomber, T., Strittmatter, K., Stacker, S.A., Achen, M.G., Alitalo, K., Christofori, G. Am. J. Pathol. (2007)
- Peutz-Jeghers syndrome: clinicopathology and molecular alterations. McGarrity, T.J., Amos, C. Cell. Mol. Life Sci. (2006)
- Retinosomes: new insights into intracellular managing of hydrophobic substances in lipid bodies. Imanishi, Y., Gerke, V., Palczewski, K. J. Cell Biol. (2004)
- Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation. Sztalryd, C., Xu, G., Dorward, H., Tansey, J.T., Contreras, J.A., Kimmel, A.R., Londos, C. J. Cell Biol. (2003)
- Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity. Tansey, J.T., Sztalryd, C., Gruia-Gray, J., Roush, D.L., Zee, J.V., Gavrilova, O., Reitman, M.L., Deng, C.X., Li, C., Kimmel, A.R., Londos, C. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Reproduction study of carteolol hydrochloride in mice. Part 2. Peri -and postnatal toxicity. Tamagawa, M., Numoto, T., Tanaka, N., Nishino, H. The Journal of toxicological sciences. (1979)
- Perilipin promotes hormone-sensitive lipase-mediated adipocyte lipolysis via phosphorylation-dependent and -independent mechanisms. Miyoshi, H., Souza, S.C., Zhang, H.H., Strissel, K.J., Christoffolete, M.A., Kovsan, J., Rudich, A., Kraemer, F.B., Bianco, A.C., Obin, M.S., Greenberg, A.S. J. Biol. Chem. (2006)
- Control of Adipose Triglyceride Lipase Action by Serine 517 of Perilipin A Globally Regulates Protein Kinase A-stimulated Lipolysis in Adipocytes. Miyoshi, H., Perfield, J.W., Souza, S.C., Shen, W.J., Zhang, H.H., Stancheva, Z.S., Kraemer, F.B., Obin, M.S., Greenberg, A.S. J. Biol. Chem. (2007)
- Identification of Mouse Prp19p as a Lipid Droplet-associated Protein and Its Possible Involvement in the Biogenesis of Lipid Droplets. Cho, S.Y., Shin, E.S., Park, P.J., Shin, D.W., Chang, H.K., Kim, D., Lee, H.H., Lee, J.H., Kim, S.H., Song, M.J., Chang, I.S., Lee, O.S., Lee, T.R. J. Biol. Chem. (2007)
- The peroxisome proliferator-activated receptor gamma regulates expression of the perilipin gene in adipocytes. Arimura, N., Horiba, T., Imagawa, M., Shimizu, M., Sato, R. J. Biol. Chem. (2004)
- Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes. Subramanian, V., Rothenberg, A., Gomez, C., Cohen, A.W., Garcia, A., Bhattacharyya, S., Shapiro, L., Dolios, G., Wang, R., Lisanti, M.P., Brasaemle, D.L. J. Biol. Chem. (2004)
- Functional Compensation for Adipose Differentiation-related Protein (ADFP) by Tip47 in an ADFP Null Embryonic Cell Line. Sztalryd, C., Bell, M., Lu, X., Mertz, P., Hickenbottom, S., Chang, B.H., Chan, L., Kimmel, A.R., Londos, C. J. Biol. Chem. (2006)
- Regulation of adipocyte lipolysis by degradation of the perilipin protein: nelfinavir enhances lysosome-mediated perilipin proteolysis. Kovsan, J., Ben-Romano, R., Souza, S.C., Greenberg, A.S., Rudich, A. J. Biol. Chem. (2007)
- TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes. Souza, S.C., Palmer, H.J., Kang, Y.H., Yamamoto, M.T., Muliro, K.V., Paulson, K.E., Greenberg, A.S. J. Cell. Biochem. (2003)
- Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system. Souza, S.C., Muliro, K.V., Liscum, L., Lien, P., Yamamoto, M.T., Schaffer, J.E., Dallal, G.E., Wang, X., Kraemer, F.B., Obin, M., Greenberg, A.S. J. Biol. Chem. (2002)
- ADRP stimulates lipid accumulation and lipid droplet formation in murine fibroblasts. Imamura, M., Inoguchi, T., Ikuyama, S., Taniguchi, S., Kobayashi, K., Nakashima, N., Nawata, H. Am. J. Physiol. Endocrinol. Metab. (2002)
- Overexpression of leptin in transgenic mice leads to decreased basal lipolysis, PKA activity, and perilipin levels. Ke, Y., Qiu, J., Ogus, S., Shen, W.J., Kraemer, F.B., Chehab, F.F. Biochem. Biophys. Res. Commun. (2003)
- The central domain is required to target and anchor perilipin A to lipid droplets. Garcia, A., Sekowski, A., Subramanian, V., Brasaemle, D.L. J. Biol. Chem. (2003)
- Magnolol stimulates lipolysis in lipid-laden RAW 264.7 macrophages. Chen, J.S., Chen, Y.L., Greenberg, A.S., Chen, Y.J., Wang, S.M. J. Cell. Biochem. (2005)
- Modulatory influence of Rosemarinus officinalis on DMBA-induced mouse skin tumorigenesis. Sancheti, G., Goyal, P. Asian Pac. J. Cancer Prev. (2006)