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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Cytotoxic constituents of Isodon rubescens var. lushiensis.

Five new ent-kaurane diterpenoids, ludongnins F-J (1-5), along with 10 known compounds, guidongnins A-C (6-8), angustifolin (9), 6-epiangustifolin (10), sculponeatin J (11), gardenin D, 5,3',4'-trihydroxy-6,7,8-trimethoxyflavone, pedalitin, and quercetin, were isolated from the leaves of Isodon rubescens var. lushiensis. The structures of 1-5 were determined by spectroscopic analysis, as well as X-ray crystallographic analysis of 1. Compounds 1-11 were evaluated against K562 leukemia cells for their cytotoxic effects.[1]

References

  1. Cytotoxic constituents of Isodon rubescens var. lushiensis. Han, Q.B., Zhao, A.H., Zhang, J.X., Lu, Y., Zhang, L.L., Zheng, Q.T., Sun, H.D. J. Nat. Prod. (2003) [Pubmed]
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